Therapeutic Group

Indication Dosage

Pain: 

By Sc Inj: 

• Child 1 - 5 Months: Initially 100 - 200 Mcg/kg Every 6 Hrs. 
• Child 6 Months - 1 Yr: Initially 100 - 200 Mcg/kg Every 4 Hrs. 
• Child 2 - 11 Yrs: Initially 200 Mcg/kg Every 4 Hrs. 
• Child 12 - 17 Yrs: Initially 2.5 - 10 Mg Every 4 Hrs. Doses To Be Adjusted According To Response 

By IV Inj: 

• Child 1 - 5 Months: 100 Mcg/kg Every 6 Hrs, 
• Child 6 Months - 11 Yrs: 100 Mcg/kg Every 4 Hrs. 
• Child 12 - 17 Yrs: 5 Mg Every 4 Hrs. Dose To Be Adjusted According To Response, Dose To Be Administered Over At Least 5 Minutes. 
• Oral Or By Rectum Child 1 - 2 Months: Initially 50 - 100 Mcg/kg Every 4 Hrs, 
• Child 3 - 5 Months: 100 - 150 Mcg/kg Every 4 Hrs, 
• Child 6 - 11 Months: 200 Mcg/kg Every 4 Hours, 
• Child 1 Yr: Initially 200 - 300 Mcg/kg Every 4 Hrs, 
• Child 2 - 11 Yrs: Initially 200 - 300 Mcg/kg Every 4 Hrs (max. Per Dose 10 Mg), 
• Child 12 - 17 Yrs: Initially 5 - 10 Mg Every 4 Hrs. Dose To Be Adjusted Adjusted According To Response 

Acute Pain: 

Oral, 

By Sc Inj, Or By IM Inj: 

• Adult: Initially 10 Mg Every 4 Hours, Adjusted According To Response. 
• Elderly And Frail Patients: Initially 5 Mg Every 4 Hrs, Adjusted According To Response. Subcutaneous Injection Not Suitable For Oedematous Patients, Dose Can Be Given More Frequently During Titration. 

By Slow IV Inj: 

• Adult: Initially 5 Mg Every 4 Hrs, Adjusted According To Response, Dose Can Be Adjusted More Frequently During Titration, Reduced Dose In Frail And Elderly Patients 

Chronic Pain: 

Oral: 

By Sc Inj, Or By IM Inj: 

• Adult: Initially 5 - 10 Mg Every 4 Hrs, Adjusted According To Response, Subcutaneous Injection Not Suitable For Oedematous Patients 

By Rectum: 

• Adult: Initially 15 - 30 Mg Every 4 Hrs, Adjusted According To Response 

Pain (with Modified-Release 12-hourly): 

• Adult: Mr Tab Every 12 Hrs, Dose Adjusted According To Daily Morphine Requirements Pain (with Modified-Release 24-hourly Preparations) 
• Adult: Mr Tab Every 24 Hours, Dose Adjusted According To Daily Morphine Requirements. 

Pain Management In Palliative Care: 

• Adult: 20 - 30 Mg Daily In Divided Doses, Using Immediate-Release Preparation 4-hourly Or A 12-hourly Modified-Release Preparation, Adjusted According To Response 

Premedication: 

By Sc Inj, Or By IM Inj: 

• Adult: Up To 10 Mg, Administered 60 - 90 Mins Before Operation 

Myocardial Infarction: 

By Slow IV Inj: 

• Adult: 5 - 10 Mg, Followed By 5 - 10 Mg If Required, Administered At A Rate Of 1 - 2 Mg/minute. 
• Elderly: 2.5 - 5 Mg, Followed By 2.5 - 5 Mg If Required, Administered At A Rate Of 1 - 2 Mg/minute 

Acute Pulmonary Oedema: 

By Slow IV Inj: 

• Adult: 5 - 10 Mg, Administered At A Rate Of 2 Mg/minute, 
• Elderly And Frail Patients: 2.5 - 5 Mg, Administered At A Rate Of 2 Mg/minute 

Dyspnoea At Rest In Palliative Care: 

• Adult: Initially 5 Mg Every 4 Hours, To Be Given In Carefully Titrated Doses

Content

Pregnancy

Not Recommended

Stability

Contra Indications

Precautions

Lactation

Side Effects