Nalbuphine

Therapeutic Group

Opioids

Indication Dosage

Moderate To Severe Pain, Pre-and Post-operative Analgesia: 

By IV, IM Or Sc Inj: 

  • Adults: 10-20 Mg 

Pain In Suspected Myocardial Infarction: 

By Slow IV Inj: 

  • Adults: 10-30 Mg A Repeat Dose Of 20 Mg May Be Given Within 30 Min, If Necessary. 
  • Children: Not Recommended.

Content

  • Inj 10mg /20mg: Per ml: Nalbuphine Hci 10mg /20mg.

Pregnancy

Positive Evidence Of Risk: Respiratory Depression And Withdrawal Symptoms In The Neonate; Gastric Stasis And Inhalation Pneumonia In The Mother If Opioid Analgesics Are Used During Labour And

Stability

  • Analgesic
  • Narcotic Analgesic

Contra Indications

  • Acute Respiratory Depression, Comatose Patients, Head Injury And Raised Intracranial Pressure (opioid Analgesics Interfere With Pupillary Responses Vital For Neurological Assessment), Risk Of Paralytic Ileus

Precautions

  • Acute Respiratory Depression, Comatose Patients, Head Injury And Raised Intracranial Pressure (opioid Analgesics Interfere With Pupillary Responses Vital For Neurological Assessment), Risk Of Paralytic Ileus

Lactation

  • Caution Advised

Side Effects

  • Biliary Spasm
  • Bradycardia
  • Confusion
  • Constipation
  • Dependence
  • Difficulty With Micturition
  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Dysphoria
  • Euphoria
  • Flushing
  • Hallucinations
  • Headache
  • Hypotension And Muscle Rigidity (larger Doses)
  • Miosis
  • Nausea
  • Oedema
  • Palpitation
  • Postural Hypotension
  • Pruritus
  • Rash
  • Respiratory Depression (larger Doses)
  • Sexual Dysfunction
  • Sleep Disturbances
  • Sweating
  • Tachycardia
  • Ureteric Spasm
  • Urinary Retention
  • Urticaria
  • Vertigo
  • Visual Disturbances
  • Vomiting
  • Adrenal Insufficiency And Hyperalgesia (long-term Use)
  • Hypogonadism (long-termuse)

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