Perindopril And Indapamide

Therapeutic Group

Ace Inhibitor

Indication Dosage

Hypertension Not Adequately Controlled By Perindopril Alone: 

  • Adults: 1 Tab Daily In The Morning Before Food. 
  • Children: Not Recommended.

Content

  • Tab 2 /0.625mg: Perindopril 2mg (as Terbutyl-amine), Indapamide 0.625mg.
  • Tab 4 /1.25mg: Perindopril 4mg (as Terbutylamine), Indapamide 1.25mg.
  • Tab 5 /1.25mg: Perindopril 5mg (as Arginine),

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Ace Inhibitor
  • Diuretic

Contra Indications

  • History Of Angioneurotic Oedema Associated With Ace Therapy, Hereditary Or Idiopathic Angioneu-rotic Oedema, Severe Renal Or Hepatic Failure, Renal Artery Stenosis, Hyperkalaemia/hypokalaemia, Hepatic Encephalopathy, Sulphonamide Sensitivity, Haemodialysis Uncompensated Heart Failure.

Precautions

  • History Of Angioneurotic Oedema Associated With Ace Therapy, Hereditary Or Idiopathic Angioneu-rotic Oedema, Severe Renal Or Hepatic Failure, Renal Artery Stenosis, Hyperkalaemia/hypokalaemia, Hepatic Encephalopathy, Sulphonamide Sensitivity, Haemodialysis Uncompensated Heart Failure.

Lactation

  • Not Recommended.

Side Effects

  • Headache
  • Oedema
  • Fatigue
  • Nausea
  • Gi Upset
  • Flushing And Dizziness
  • Rash
  • Gingival Hyperplasia
  • Mood Changes
  • Dry Mouth
  • Palpitations
  • Dyspnoea
  • Muscle Cramps
  • Asthenia
  • Rarely
  • Alopecia
  • Pruritus
  • Angioedema
  • Somnolence
  • Myalgia
  • Arthralgia
  • Peripheral Neuropathy
  • Pancreatitis
  • Increased Micturition
  • Hyperglycaemia
  • Impotence
  • Sweating
  • Syncope
  • Thrombocytopenia
  • Vasculitis
  • Visual Disturbances
  • Asthenia
  • Mild Cough
  • Decreases In Haemoglobin
  • Red Cells And Platelets Counts
  • Reversible Increase In Blood Urea And Creatinine
  • Proteinuria.