Pioglitazone
Therapeutic Group
Blood Glucose Lowering Drugs, Excluding InsulinIndication Dosage
Type 2 Diabetes Mellitus (alone Or Combined With Metformin Or Sulfonylurea, Or With Both, Or With Insulin):
- Adult: Initially 15-30 Mg Once Daily, Adjusted According To Response To 45 Mg Once Daily, In Elderly Patients, Initiate With the Lowest Possible Dose And Increase Gradually; Review Treatment After 3-6 Months And Regularly Thereafter For Risk-benefits Assessment. The dosage Of Concomitant Sulfonylurea Or Insulin May Need To Be Reduced.
- Children: Not Recommended.
Content
- Tab 15mg /30mg /45mg: Pioglita Zone (as Nci) 15mg /50mg /45mg.
Pregnancy
Contraindicated Or Not Recommended
Stability
- Thiazolidinedione
Contra Indications
- History Of Heart Failure, Previous Or Active Bladder Cancer, Uninvestigated Macroscopic Haematuria, Dialysis, Diabetic Ketoacidosis, Pregnancy And Lactation.
Precautions
- History Of Heart Failure, Previous Or Active Bladder Cancer, Uninvestigated Macroscopic Haematuria, Dialysis, Diabetic Ketoacidosis, Pregnancy And Lactation.
Lactation
- Contraindicated or Not Recommended.
Side Effects
- Gi Disturbances
- Anaemia
- Arthralgia
- Dizziness
- Haematuria
- Headache
- Hypoaesthesia
- Impotence
- Oedema
- Vertigo
- Visual Disturbances
- Weight Gain
- Altered Blood Lipids
- Bladder Cancer
- Fatigue
- Hypoglycaemia
- Insomnia
- Proteinuria
- Sweating
- Rare: Liver Dysfunction.