Pyridostigmine Bromide

Therapeutic Group

Other Nervous System Drugs

Indication Dosage

Pyridostigmine bromide is a medication primarily indicated for the treatment of myasthenia gravis, a neuromuscular disorder characterized by muscle weakness and fatigue. It works by enhancing the communication between nerve cells and muscles, helping to improve muscle strength and control in individuals with this condition.

Myasthenia Gravis: 

  • Adult: 30-120 Mg, Doses To Be Given At Suitable Intervals Throughout Day; Usual Dose0.3-1.2 G Daily In Divided Doses. Consider Immunosuppressant Therapy If the Total Daily Dose Exceeds 360 Mg, Down-regulation Of Acetylcholine Receptors is Possible If the Total Daily Dose Exceeds 450 Mg 
  • Children - Neonate: Initially 1-1.5 Mg/kg, Increased Gradually To Max 10 Mg, Repeated Throughout The Day, Give 30-60 Minutes Before Feeds; 
  • 1 Month-12 Yr: Initially 1-1.5 Mg/kg/day, Increased Gradually To 7 Mg/kg/day In 6 Divided Doses; Usual Total Daily Dose 30-360 Mg; 
  • 12-18 Yr: 30-120 Mg, Repeated Throughout The Day; Usual Total Daily Dose 300-600 Mg. Consider Immunosuppressant Therapy If the Total Daily Dose Exceeds 360 Mg, Down-regulation Of Acetylcholine Receptors is Possible If the Total Daily Dose Exceeds 450 Mg. 

Paralytic ileus: 

  • Adult: 60-240 Mg As Required.

Content

  • Tab 60mg: Pyridostigmine Bromide 60mg.

Pregnancy

Caution Advised Or Avoid

Stability

  • Anticholinesterase

Contra Indications

  • Intestinal Or Urinary Obstruction.

Precautions

  • Intestinal Or Urinary Obstruction.

Lactation

  • Contraindicated or Avoid

Side Effects

  • Abdominal Cramps
  • Diarrhoea
  • Increased Salivation
  • Nausea

Available Brands