Ranolazine

Therapeutic Group

Cardiac Therapy

Indication Dosage

Ranolazine is a prescription medication primarily indicated for the treatment of chronic angina, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle. It is typically prescribed when other angina medications have not provided sufficient relief or when additional treatment options are necessary to manage the symptoms of angina. Ranolazine works by improving blood flow to the heart and reducing the frequency of angina attacks, helping patients with this condition lead a more comfortable and active life.

As Adjunctive Therapy In The Treatment Of Stable Angina Inpatients Inadequately Controlled Or Intolerant Of First-line Anti-anginal Therapies 

  • Adult: Initially 375 Mg Twice Daily For 2-4 Weeks, Then Increased To 500 Mg Twice Daily, Then Adjusted According To Response To 750 Mg Twice Daily; Reduced If Not Tolerated To 375-500 Mg Twice Daily 
  • Children: Not Recommended.

Content

  • Tab 500mg /1000mg: Ranolazine 500mg /1000mg.

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Anti-anginal Piperazine Derivatives

Contra Indications

  • Severe Renal Impairment.

Precautions

  • Severe Renal Impairment.

Lactation

  • Not Recommended.

Side Effects

  • Asthenia
  • Constipation
  • Dizziness
  • Headache
  • Nausea
  • Vomiting
  • Abdominal Pain
  • Anorexia
  • Anxiety
  • Chromaturia
  • Confusion
  • Cough
  • Dehydration
  • Drowsiness
  • Dry Mouth
  • Dyspepsia
  • Dysponea
  • Dysuria
  • Epistaxis
  • Flatulence
  • Haematuria
  • Hallucination
  • Hot Flush
  • Hypoaesthesia
  • Hypotension
  • Insomnia
  • Joint Swelling
  • Lethargy
  • Muscle Cramp
  • Pain In Extremities
  • Peripheral Oedema
  • Prolonged Qt Interval
  • Pruritus
  • Sweating
  • Syncope
  • Tinnitus
  • Tremor
  • Visual Disturbance