Ribavirin

Therapeutic Group

Anti-virals For Systemic Use

Indication Dosage

Ribavirin is a medication used to treat certain viral infections, particularly Hepatitis C. It helps your body fight the virus and may be used in combination with other medicines to improve the chances of a cure.

Chronic Hepatitis C In Combination With Direct Acting Antivirals, Or Interferon Alfa 2a, Or Peginterferon Alfa 2a: 

  • Adult (body weight Up To 75 Kg): 400 Mg, Dose To Be Taken In The Morning And 600 Mg, Dose To Be Taken In The Evening; (body weight 75 Kg And Above): 600 Mg Twice Daily 
  • Children: 15-20 Mg/kg Body Weight Daily In Three Divided Dose For 5-7 Days. 

Chronic Hepatitis C Genotype 2 Or 3 (not Previously treated), Or Patients Infected With Hiv And Hepatitis C (In Combination With Peginterferon Alfa): 

  • Adult: Usual Dose 400 Mg Twice Daily

Content

  • Cap /Tab 100mg /200mg / 400mg /500mg /600mg: Ribavirin 100mg /200mg / 400mg /500mg /600mg.
  • Syp 50mg /100mg: Per 5 ml: Ribavirin 50mg /100mg.

Pregnancy

Contraindicated

Stability

  • Anti-cytomegalovirus Agent

Contra Indications

  • Renal Impairment, Severe Hepatic Dysfunction Or Decompensated Cirrhosis, Autoimmune Disease (including Autoimmune Hepatitis), History Of Severe Psychiatric Condition, Severe Cardiac Disease, Unstable Or Uncontrolled Cardiac Disease In Previous 6 Months, Haemoglobinopathies, Severe Debilitating Medical Conditions.

Precautions

  • Renal Impairment, Severe Hepatic Dysfunction Or Decompensated Cirrhosis, Autoimmune Disease (including Autoimmune Hepatitis), History Of Severe Psychiatric Condition, Severe Cardiac Disease, Unstable Or Uncontrolled Cardiac Disease In Previous 6 Months, Haemoglobinopathies, Severe Debilitating Medical Conditions.

Lactation

  • Contraindicated

Side Effects

  • Gi Disturbance
  • Alopecia
  • Angina
  • Anorexia
  • Anxiety
  • Aplastic Anaemia
  • Arrhythmias
  • Arthralgia
  • Asthenia
  • Ataxia
  • Bipolar Disorders
  • Cardiomyopathy
  • Cerebral Haemorrhage
  • Cerebral Ischaemia
  • Cheilitis
  • Chest Pain
  • Colitis
  • Dehydration
  • Depression
  • Diabetes
  • Dizziness
  • Dry Eyes Mouth
  • Dyspepsia
  • Dysphagia
  • Dysphonia
  • Dyspnea
  • Earache
  • Endocarditis
  • Epistaxis
  • Flushing
  • Gi Bleeding
  • Gastroesophageal Reflux
  • Gingival Bleeding
  • Gingivitis
  • Glossitis
  • Growth Retardation
  • Haemolyticanaemia
  • Hallucination
  • Headache
  • Hearing Impairment Or Loss
  • Hyperaesthesia
  • Hyperglycaemia
  • Hyperkinesia
  • Hypertonia
  • Hypertriglyceridaemia
  • Hyperuricaemia
  • Hypoaesthesia
  • Hypocalcaemia
  • Influenza-like Symptoms
  • Interstitial Pneumonitis
  • Leucopenia
  • Lymphadenopathy
  • Malaise
  • Mania
  • Menstrual Disturbance
  • Micturition Disorders
  • Musculoskeletal Pain
  • Myalgia
  • Myocardial Infarction
  • Myositis
  • Neutropenia
  • Optic Neuropathy
  • Oral Candidiasis
  • Palpitation
  • Pancreatitis
  • Paraesthesia
  • Mouth & Peptic Ulcer
  • Pericarditis
  • Peripheral Ischaemia
  • Peripheral Neuropathy
  • Peripheral Oedema
  • Photosensitivity
  • Prostatitis
  • Pruritus
  • Psoriasis
  • Psychotic Disorders
  • Pulmonary Embolism
  • Rash
  • Renal Failure
  • Respiratory Infections
  • Retinal Detachment
  • Retinal Haemorrhage
  • Rhabdomyolysis
  • Rheumatoid Arthritis
  • Sarcoidosis
  • Seizures
  • Skin Discoloration
  • Stevens-johnson Syndrome
  • Stomatitis
  • Suicidal Ideation
  • Syncope
  • Systemic Lupus Erythematosus
  • Tachycardia
  • Tachypnea
  • Thrombocytopenia
  • Thrombocytopenia Purpura
  • Thyroid Disorders
  • Tinnitus
  • Tongue Pigmentation
  • Tooth Disorder
  • Toxic Epidermal Necrolysis
  • Tremor
  • Urinary Tract Infections
  • Vaculitis
  • Vertigo
  • Virilism
  • Visual Disturbances
  • Wheezing

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