Rosiglitazone
Therapeutic Group
Blood Glucose Lowering Drugs, Excluding InsulinIndication Dosage
Type 2 Diabetes Mellitus (as Monotherapy Or In Combination With Sulphonylureas Or Metformin When Metformin Alone Is Inadequate):
- Adults: Initial: 2 Mg Twice Daily Or 4 Mg Once Daily. Titrate: May Increase After 8-12 Weeks To 4 Mg Twice Daily Or 8 Mg Once Daily. Max: 8 Mg/day As Monotherapy Or With Metformin, Sulfonylureas, Or Sulfonylureas Plus Metformin; 4 Mg/day With Insulin. Decrease Insulin By 10-25% If Fasting Plasma Glucose < 100 Mg/dl; Adjusted According To Response.
- Children: Not Recommended.
Content
- Tab 2mg /4mg /8mg: Rosiglitazone 2mg /4mg /8mg.
Pregnancy
Not Recommended.
Stability
- Thiazolidinedione
Contra Indications
- Hepatic Impairment Raised Liver Enzymes, Cardiac Failure Or History Of Cardiac Failure, Pregnancy And Lactation.
Precautions
- Hepatic Impairment Raised Liver Enzymes, Cardiac Failure Or History Of Cardiac Failure, Pregnancy And Lactation.
Lactation
- Contraindicated or Not Recommended.
Side Effects
- Gi Upset
- Anaemia
- Headache
- Fatigue
- Oedema
- Hypercholesterolaemia
- Hypoglycaemia
- Weight Gain.