Roxadustat

Therapeutic Group

Anti-Anemic Preparations (Erythropoietin Products)

Indication Dosage

Indication:
Roxadustat is used for the treatment of anemia caused by chronic kidney disease (CKD) in both dialysis and non-dialysis patients. It works by stimulating the body’s natural production of erythropoietin (EPO) to increase red blood cell levels.

Dosage:

  • Adults (Non-Dialysis Patients): 70–100 mg orally three times a week (adjusted based on hemoglobin levels).
  • Adults (Dialysis Patients): 100–120 mg orally three times a week (dose adjustments as needed).
  • Dosage varies based on weight, hemoglobin levels, and Medical Condition, so it should be used under a doctor's supervision.

Content

  • Tab 20mg/50mg/70mg/100mg/150mg: Roxadustat

Pregnancy

Not Recommended

Stability

  • Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PH) Inhibitors

Contra Indications

  • Roxadustat is contraindicated in patients with uncontrolled high blood pressure, active blood clotting disorders, severe liver disease, or a history of serious allergic reactions to the drug. It should also be avoided in pregnant and breastfeeding women unless prescribed by a doctor.

Precautions

  • Roxadustat is contraindicated in patients with uncontrolled high blood pressure, active blood clotting disorders, severe liver disease, or a history of serious allergic reactions to the drug. It should also be avoided in pregnant and breastfeeding women unless prescribed by a doctor.

Lactation

  • Avoid

Side Effects

  • High blood pressure
  • Headache
  • Nausea
  • Vomiting
  • Diarrhea
  • Swelling (Edema)
  • Increased risk of blood clots
  • Dizziness
  • Fatigue
  • Hyperkalemia (High potassium levels)
  • Chest pain (rare, but serious)

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