Sertraline

Therapeutic Group

Anti-depressants

Indication Dosage

Sertraline is part of a group of medicines called antidepressants, and it's used to treat conditions like depression, anxiety disorders, and sometimes even panic disorders.

Depressive Illness: 

  • Adult: Initially 50 Mg Daily, Then Increased In Steps Of 50 Mg At Intervals Of At Least 1 Week If Required; Maintenance 50 Mg Daily; Maximum 200 Mg Per Day 

Obsessive-compulsive Disorder: 

  • Adult: Initially 50 Mg Daily, Then Increased In Steps Of 50 Mg At Intervals Of At Least 1 Week If Required; Maintenance 50 Mg Daily; Maximum 200 Mg Per Day 
  • Children 6-12 Yrs: Initially 25 Mg Daily Increased To 50 Mg Daily After 1 Week, Further Increased If Necessary In Steps Of 50 Mg At Intervals Of At Least 1 Week, Max 200 Mg Daily;
  • 12-18 Yrs: Initially 50 Mg Daily Increased If Necessary In Steps Of 50 Mg Over Several Wk, Max 200 Mg Daily. 

Panic Disorder, Post-traumatic Stress Disorder, Social Anxiety Disorder: 

  • Adult: Initially 25 Mg Daily For 1 Week, Then Increased To 50 Mg Daily, Then Increased In Steps Of 50 Mg At Intervals Of At Least 1 Week If Required, Increase Only If Response Is Partial And If Drug Is Tolerated; Maximum 200 Mg Per Day 

Premenstrual Dysphoric Disorder: 

  • Adult: Initially 50 Mg Once Daily Continuous Or Limit To Luteal Cycle Phase, Increase By 50 Mg/cycle Up To 150 Mg/ Day For Continuous Or 100 Mg/day For Luteal Phase Dosing For 3 Days At Beginning Of Each Luteal Phase Dosing Period.

Content

  • Tab 50mg /100mg: Sertraline (as Hci) 50mg /100mg.

Pregnancy

Avoid Unless Potential Benefit Outweighs Risk

Stability

  • SSRIs

Contra Indications

  • Severe Hepatic Impairment, Unstable Epilepsy. Within 2 Weeks Of Stopping Maols Or 7 Days Of Stopping Moclobemide.

Precautions

  • Severe Hepatic Impairment, Unstable Epilepsy. Within 2 Weeks Of Stopping Maols Or 7 Days Of Stopping Moclobemide.

Lactation

  • Caution Advised or Avoid

Side Effects

  • Aggression
  • Anorexia
  • Amnesia
  • Agitation
  • Bruxism
  • Bronchospasm
  • Hepatitis
  • Hypercholesterolaemia
  • Hyperprolactinaemia
  • Hypertension
  • Hypoglycaemia
  • Hypothyroidism
  • Jaundice
  • Leucopenia
  • Liver Failure
  • Menstrual Irregularities
  • Palpitation
  • Pancreatitis
  • Paraesthesia
  • Postural Hypotension
  • Stomatitis
  • Tachycardia
  • Tinnitus
  • Urinary Incontinence
  • Gi Disturbance
  • Sexual Dysfunction
  • Tremor
  • Increases Sweating
  • Akathisia
  • Pharyngitis
  • Nightmares
  • Dysgeusia
  • Tinnitus
  • Chest Pain
  • Paraesthesia
  • Hypertonia
  • Disturbed Attention
  • Hot Flushes
  • Dizziness
  • Insomnia
  • Somnolence
  • Malaise
  • Arthralgia
  • Myalgia
  • Rash
  • Anaphylactoid Reactions
  • Angioedema
  • Visual Disturbances
  • Headache
  • Panic Reactions
  • Drowsiness
  • Nervousness
  • Urinary Retention
  • Seizures
  • Psychosis.
  • Rare: Erythema
  • Multiforme
  • Hyponatraemia
  • Activation Of Mania/hypomania
  • Altered Platelet Function
  • Withdrawal Symptoms.

Available Brands