Simvastatin And Ezetimibe
Therapeutic Group
Lipid Modifying AgentsIndication Dosage
Homozygous Familial Hypercholesterolaemia, Primary Hypercholesterolaemia, And Mixed Hyperlipidaemia In Patients Stabilised On The Individual Components In The Same Proportions, Or For Patients Not adequately Controlled By Statin Alone:
- Adults: 1 Tab Of 10/20 Mg As a Single Dose In the Evening. Adjust At Minimum 4 Wk Intervals According To Response, Max 10 Mg Ezetimibe And 80 Mg Simvastatin Daily.
- Children: Not Recommended.
Content
- Tab 10 /10mg: Simvastatin 10mg, Ezetimibe 10mg.
- Tab 20 /10mg: Simvastatin 20mg, Ezetimibe 10mg.
- Tab 40 /10mg: Simvastatin 40mg, Ezetimibe 10mg.
- Tab 80 /10mg: Simvastatin 80mg, Ezetimibe 10mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Cholesterol Absorption Inhibitor
- Statin
Contra Indications
- Active Liver Disease, Moderate Or Severe Liver Impairment.
Precautions
- Active Liver Disease, Moderate Or Severe Liver Impairment.
Lactation
- Not Recommended.
Side Effects
- Headache
- Flatulence
- Myalgia
- Abdominal Pain
- Diarrhoea
- Fatigue.