Streptokinase

Therapeutic Group

Anti-thrombotic Agents

Indication Dosage

Streptokinase is used to treat serious blood clots in the body. It helps dissolve these clots and can be a lifesaving treatment for conditions like heart attacks, strokes, and deep vein thrombosis (DVT). It's like a "clot buster" that helps restore normal blood flow, preventing damage to vital organs and improving your chances of recovery. Always use it under a doctor's guidance.

Acute Myocardial Infarction: 

  • Adult: 1 500 000 Units, Dose To Be Given Over 60 Minutes, within 12 Hours Of Onset Of Symptom. 

Deep-vein thrombosis, Pulmonary Embolism, Acute Arterial Thromboembolism, Central Retinal Venous Or Arterial Thrombosis: 

  • Adult: 250 000 Units, Dose To Be Given Over 30 Minutes, Then 100 000 Units Every 1 Hour For Up To 12-72 Hours, According To Condition With Monitoring Of Clotting Parameters (consult Product Literature) Acute Pulmonary Embolism: 3 Million Unit Dose Over 24 Hr.

Content

  • Inj: Streptokinase 1.5 Miu Per Vial (Powder)
  • Inj: Per Vial: Streptokinase 100000 Iu /250000 Iu /600000 Iu /750000 Iu Powder In Vials.

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Fibrinolytic

Contra Indications

  • Allergy And Cross-sensitivity; Contra-indicated If Previous Allergic Reaction To Streptokinase, Recent Streptokinasetherapy (5 Days Streptokinasepreviously), Severe Liver Or Kidney Damage, Recent Haemorrhage, Haemorrhagic Diathesis, Severe Hypotension, Streptococcal Infections, Sub-acute Bacterial Endocarditis, Recent Surgery, Bleeding Tendencies.

Precautions

  • Allergy And Cross-sensitivity; Contra-indicated If Previous Allergic Reaction To Streptokinase, Recent Streptokinasetherapy (5 Days Streptokinasepreviously), Severe Liver Or Kidney Damage, Recent Haemorrhage, Haemorrhagic Diathesis, Severe Hypotension, Streptococcal Infections, Sub-acute Bacterial Endocarditis, Recent Surgery, Bleeding Tendencies.

Lactation

  • Caution Advised or Effect Undetermined

Side Effects

  • Hypotension
  • Arrhythmias
  • Febrile Reactions
  • Rare; Anaphylaxis Hemorrhage.

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