Tranexamic Acid

Therapeutic Group

Anti-hemorrhagic

Indication Dosage

Tranexamic Acid is a medication used to stop or reduce excessive bleeding in various situations. It can be helpful for:

  • Menstrual Bleeding: It's used to treat heavy menstrual periods, making them more manageable.
  • Surgeries: Doctors use it during surgeries to reduce bleeding, especially in procedures like orthopedic surgeries, heart surgeries, and dental extractions.
  • Trauma and Injuries: Tranexamic Acid can be given to people with traumatic injuries to control bleeding.
  • Nosebleeds: It's also used in some cases to stop nosebleeds that are hard to control.

 

Local Fibrinolysis To Prevent Bleeding: 

Oral: 

  • Adults: 15-25 Mg/kg Body Weight Two - Three Times Daily. 

By Slow IV Inj: 

  • 0.5-1 Gm Slow IV Injection 3 Times Daily. 

Menorrhagia: 

  • Adult: 1-1.5 Gm 3-4 Times Daily, Initiated When Heavy Bleeding Started, For 3-4 Days. 

Hereditary Angioedema: 

  • Adult: 1-1.5 Gm 2-3 Times Daily. 

General Fibrinolysis: 

  • Adult: 1 Gm (or 15 Mg/kg)every 6-8 Hr. 

Inhibition Of Fibrinolysis, Hereditary Angioedema: 

Oral: 

  • Children 1 Mth-18 Yr: 15-25mg/kg (max 1.5 Gm) 2-3 Times Daily. 

By IV Inj: 

  • Children 1-18 Yr: 10 Mg/kg (max 1 G,) 2-3 times Daily IV Injection Over At Least 10minutes. 

By Continuous IV Infusion: 

  • Adult: 45 Mg/kg Over 24 Hr. 
  • Not Recommended For Children Below 1 Year Of Age. 

Prevention Of Excessive Bleeding After Dental Procedures (in haemophiliac): 

By IV Inj: 

  • Pre-operatively, Children 6-18 Yrs: 10 Mg/kg (max 1.5 Gm). 

Oral: 

  • Pre-Operatively, Children 6-18 Yrs: 15-25 Mg/kg (max 1.5 Gm). 
  • Postoperatively, Children 6-18 Yr: 15-25 Mg/kg (max 1.5 Gm) 2-3 Times Daily Forup To 8 Days.

Content

  • Tab /Cap 250mg /500mg: Tranexamic Acid 250mg /500mg.
  • Inj 100mg /250mg /500mg Per ml: Tranexamic Acid 100mg /250mg /500mg

Pregnancy

Caution Advised, Avoid

Stability

  • Fibrinolytic
  • Haemostatic

Contra Indications

  • Thromboembolism, Renal Disease, Color Blindness, Haematuria.

Precautions

  • Thromboembolism, Renal Disease, Color Blindness, Haematuria.

Lactation

  • Caution Advised

Side Effects

  • Renal Failure
  • Myopathy
  • Intracranial Thrombosis
  • Gastrointestinal Disorders
  • Nausea
  • Vomiting
  • Diarrhoea
  • Purpura
  • Colour Vision Disturbances (discontinue) Giddiness On Rapid Iv Injection.

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