Triptorelin

Therapeutic Group

Pituitary And Hypothalamic Hormones And Analogues

Indication Dosage

Endometriosis: 

By IM Inj:

  • Adult (Female): Start During the First 5 Days Of the Cycle. 3.75 Mg Every 28 Days For Max 6 Months 

Treatment Of Uterine Fibroids Prior To Surgery Is Inappropriate: 

By IM Inj:

  • Adult (Female): Start During First 5 Days Of Cycle 3.75 Mg Every 28 Days For Minimum of 3 Months. Consider Uterine Leiomyosarcoma If No Change Or An Increase In Uterine Volume 

Advanced Prostatic Cancer: 

By IM Inj: 

  • Adult (Male): 3.75 Mg Every 28 Days. See Literature. 

Gonadotrophin-dependent Precocious Puberty: 

By IM Inj: 

  • Decapeptyl: 11.25 Mg Every 3 Months. 

By Sc Or IM Inj: 

  • Gonapeptyl: Body-weight Under 20 Kg: Initially 1.875 Mg On Days 0,14, And 28, Then 1.875 Mg Every 4 Weeks; Body-weight 20-30 Kg: Initially 2.5 Mg On Days 0, 14, And 28, Then 2.5 Mg Every 4 Week; Body-weight Over 30 Kg: Initially 3.75 Mg On Days 0, 14, And 28, Then 3.75 Mg Every 4 Week; Discontinue When Bone Maturation Consistent With Age Above12 Yr In Girls And Above 13 Yr In Boys, May Be Given Every 3 Week If Necessary.

Content

  • Long Acting Inj 3.75mg /Short Acting Inj 0.1mg: Triptorelin 3.75mg /0.1mg; Powder For Reconstitution.

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Gonadotrophin Releasing Hormones Analogue

Contra Indications

  • In Endometriosis Do Not Use For Longer Than 6 Months (do Not Repeat), Undiagnosed Vaginal Bleeding, Spinal Cord Compression, Spinal Metasta-ses,

Precautions

  • In Endometriosis Do Not Use For Longer Than 6 Months (do Not Repeat), Undiagnosed Vaginal Bleeding, Spinal Cord Compression, Spinal Metasta-ses,

Lactation

  • Contraindicated, Avoid

Side Effects

  • Anaphylaxis
  • Arthralgia
  • Asthenia
  • Asthma
  • Breast Tenderness (males And Females)
  • Changes In Blood Pressure
  • Changes In Breast Size
  • Changes In Scalp And Body Hair
  • Depression Gi Disturbances
  • Headache
  • Hot Flushes
  • Hypersensitivity Reactions
  • Increased Sweating
  • Local Reactions At Injection Site
  • Mood Changes
  • Ovarian Cysts (consider Withdrawal)
  • Paraesthesia
  • Pruritus
  • Rash
  • Urticaria
  • Visual Disturbances
  • Weight Changes

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