Triptorelin
Therapeutic Group
Pituitary And Hypothalamic Hormones And AnaloguesIndication Dosage
Endometriosis:
By IM Inj:
- Adult (Female): Start During the First 5 Days Of the Cycle. 3.75 Mg Every 28 Days For Max 6 Months
Treatment Of Uterine Fibroids Prior To Surgery Is Inappropriate:
By IM Inj:
- Adult (Female): Start During First 5 Days Of Cycle 3.75 Mg Every 28 Days For Minimum of 3 Months. Consider Uterine Leiomyosarcoma If No Change Or An Increase In Uterine Volume
Advanced Prostatic Cancer:
By IM Inj:
- Adult (Male): 3.75 Mg Every 28 Days. See Literature.
Gonadotrophin-dependent Precocious Puberty:
By IM Inj:
- Decapeptyl: 11.25 Mg Every 3 Months.
By Sc Or IM Inj:
- Gonapeptyl: Body-weight Under 20 Kg: Initially 1.875 Mg On Days 0,14, And 28, Then 1.875 Mg Every 4 Weeks; Body-weight 20-30 Kg: Initially 2.5 Mg On Days 0, 14, And 28, Then 2.5 Mg Every 4 Week; Body-weight Over 30 Kg: Initially 3.75 Mg On Days 0, 14, And 28, Then 3.75 Mg Every 4 Week; Discontinue When Bone Maturation Consistent With Age Above12 Yr In Girls And Above 13 Yr In Boys, May Be Given Every 3 Week If Necessary.
Content
- Long Acting Inj 3.75mg /Short Acting Inj 0.1mg: Triptorelin 3.75mg /0.1mg; Powder For Reconstitution.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Gonadotrophin Releasing Hormones Analogue
Contra Indications
- In Endometriosis Do Not Use For Longer Than 6 Months (do Not Repeat), Undiagnosed Vaginal Bleeding, Spinal Cord Compression, Spinal Metasta-ses,
Precautions
- In Endometriosis Do Not Use For Longer Than 6 Months (do Not Repeat), Undiagnosed Vaginal Bleeding, Spinal Cord Compression, Spinal Metasta-ses,
Lactation
- Contraindicated, Avoid
Side Effects
- Anaphylaxis
- Arthralgia
- Asthenia
- Asthma
- Breast Tenderness (males And Females)
- Changes In Blood Pressure
- Changes In Breast Size
- Changes In Scalp And Body Hair
- Depression Gi Disturbances
- Headache
- Hot Flushes
- Hypersensitivity Reactions
- Increased Sweating
- Local Reactions At Injection Site
- Mood Changes
- Ovarian Cysts (consider Withdrawal)
- Paraesthesia
- Pruritus
- Rash
- Urticaria
- Visual Disturbances
- Weight Changes