Valacyclovir

Therapeutic Group

Anti-virals For Systemic Use

Indication Dosage

Valacyclovir is a medication that is used to treat infections caused by certain viruses, mainly the herpes viruses. It's commonly prescribed for:

  • Cold Sores: Valacyclovir helps heal and reduce the pain and discomfort of cold sores (also known as oral herpes or fever blisters) that appear on or around the lips.
  • Genital Herpes: It's used to manage outbreaks of genital herpes, which can cause painful sores and discomfort in the genital and anal areas.
  • Shingles: Valacyclovir can also be used to treat shingles (herpes zoster), a painful rash that often occurs in people who have had chickenpox.
  • Preventing Herpes Outbreaks: In some cases, doctors may prescribe Valacyclovir to prevent future outbreaks of genital herpes in individuals who experience frequent recurrences.

It works by slowing down the growth and spread of the herpes virus in the body, helping to reduce symptoms and the duration of outbreaks. Always take Valacyclovir as prescribed by your healthcare provider.

Dosage:

Herpes Zoster Infection, Treatment: 

  • Adult: 1 G 3 Times A Day For 7 Days; For Treatment Of Recurrent Infections: 500 Mg Twice Daily For 3-5 Days 

Herpes Zoster Infection, Treatment In Immune-compromised Patients: 

  • Adult: 1 G 3 Times A Day For At Least 7 Days And Continued For 2 Days After Crusting Of Lesions; For Treatment Of Recurrent Infections:1 G Twice Daily For 5-10 Days 

Herpes Simplex, Treatment Of First Infective Episode: 

  • Adult: 500 Mg Twice Daily For 5 Days (longer If New Lesions Appear During Treatment Or Healing Is Incomplete) 

Herpes Simplex Infections Treatment Of First Episode In Immune-compromised Or Hiv-positive Patients: 

  • Adult: 1 G Twice Daily For 10 Days 

Herpes Labialis Treatment: 

  • Adult & Children Above 12yrs: Initially 2 G, Then 2 G After 12 Hours 

Herpes Simplex, Suppression Of Infections: 

  • Adult: 500 Mg Daily In 1-2 Divided Doses, Interrupted Every 6-12 Months To Reassess Recurrence Frequency; Consider Restarting After Two Or More Recurrences 

Herpes Simplex, Suppression Of Infections In Immune-compromised Or Hiv-positive Patients: 

  • Adult: 500 Mg Twice Daily, Interrupted Every 6-12 Months To Reassess Recurrence Frequency; Consider Restarting After Two Or More Recurrences 

Genital Herpes, Reduction Of Transmission: 

  • Adult: 500 Mg Once Daily, To Be Taken By The Infectedpartner 

Prevention Of Cytomegalovirus Disease Following Solid-organ Transplantation When Valganciclovir Or Ganciclovir CanNot Be Used: 

  • Adult: 2 G 4 Times A Day For 90 Days, Starting Within 72 Hours Of Transplantation

Content

  • Tab: Valacyclovir (as Hci) 500mg.

Pregnancy

Caution Advised

Stability

  • Dna Polymerase Inhibitor

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Caution Advised

Side Effects

  • Abdominal Pain
  • Diarrhoea
  • Fatigue
  • Headache
  • Nausea
  • Photosensitivity
  • Pruritus
  • Rash
  • Urticaria
  • Vomiting.
  • Rare: Acute Renal Failure
  • Anaemia
  • Ataxia
  • Confusion
  • Convulsions
  • Dizziness
  • Drowsiness
  • Dysarthria
  • Dyspnea
  • Hallucinations
  • Hepatitis
  • Jaundice
  • Leucopenia
  • Neurological Reactions
  • Thrombocytopenia