Valganciclovir

Therapeutic Group

Anti-virals For Systemic Use

Indication Dosage

Valganciclovir is a medication used to treat infections caused by a virus called cytomegalovirus (CMV). It is commonly prescribed for people with weakened immune systems, such as those who have had an organ transplant, to prevent or treat CMV infections. Valganciclovir helps to stop the virus from spreading and causing problems in the body.

Cytomegalovirus Retinitis, Induction And Maintenance Treatment In Patients With Aids: 

  • Adult: Initially 900 Mg Twice Daily For 21 Days, Then 900 Mg Daily, Induction Regimen May Be Repeated If Retinitis Progresses 

Prevention Of Cytomegalovirus Disease Following Solid Organ Transplantation From A Cytomegalovirus Positive Donor: 

  • Adult: 900 Mg Daily For 100 Days (for 100-200 Days Following Kidney Transplantation), To Be Started Within10 Days Of Transplantation

Content

  • Tab: Valganciclovir (as Hydrochloride) 450mg.

Pregnancy

Avoid; Teratogenic Risk

Stability

  • Dna Polymerase Inhibitor Prodrug,

Contra Indications

  • Hypersensitivity To Ganciclovir Or Acyclovir, Abnormally Low Haemoglobin, Neutrophil, Or Platelet Counts.

Precautions

  • Hypersensitivity To Ganciclovir Or Acyclovir, Abnormally Low Haemoglobin, Neutrophil, Or Platelet Counts.

Lactation

  • Contraindicated

Side Effects

  • Gi Disturbance
  • Anaemia
  • Anorexia
  • Anxiety
  • Arthralgia
  • Chestpain
  • Confusion
  • Convulsions
  • Depression
  • Dermatitis
  • Dizziness
  • Dyspepsia
  • Dysphagia
  • Dyspnea
  • Ear Pain
  • Eye Pain
  • Fatigue
  • Headache
  • Hepatic Dysfunction
  • Infection
  • Insomnia
  • Leucopenia
  • Macular Oedema
  • Myalgia
  • Pancytopenia
  • Peripheral Neuropathy
  • Pruritus
  • Pyrexia
  • Renal Impairment
  • Retinal Detachment
  • Taste Disturbance
  • Thrombocytopenia
  • Vitreous Floaters
  • Vomiting
  • Weight Loss
  • Alopecia
  • Anaphylactic Reactions
  • Arrhythmias
  • Disturbances In Hearing And Vision
  • Haematuria
  • Hypotension
  • Male Infertility
  • Mouth Ulcers
  • Pancreatitis
  • Psychosis
  • Tremor

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