Verapamil HCl

Therapeutic Group

Calcium Channel Blockers

Indication Dosage

Treatment Of Supraventricular Arrhythmias: 

  • Adult: 40-120 Mg 3 Times A Day 

By Slow IV Inj: 

  • Adult: 5-10 Mg, Given Over 2 Minutes, Preferably With ECG Monitoring 
  • Elderly: 5-10 Mg, To Be Given Over 3 Minutes, Preferably With ECG Monitoring 
  • Children 1-18 Yrs: 100-300 Mcg/kg (max 5 Mg) As A Single Dose, IV Injection Over 2-3 Minutes; Repeated After 30 Minutes If Necessary. 

Paroxysmal Tachyarrhythmias: 

By Slow IV Inj: 

  • Adult: Initially 5-10 Mg, Followed By 5 Mg After 5-10 Minutes If Required, To Be Given Over 2 Minutes, Preferably With ECG Monitoring 
  • Elderly: Initially 5-10 Mg, Followed By 5 Mg After 5-10 Minutes If Required, To Be Given Over 3 Minutes, Preferably With ECG Monitoring 

Angina: 

  • Adult: 80-120 Mg 3 Times A Day 

Hypertension: 

  • Adult: 240-480 Mg Daily In 2-3 Divided Doses 
  • Children 1-2 Yrs: 20 Mg 2-3 Times Daily; 
  • 2-18 Yrs: 40-120 Mg 2-3 Times Daily. Modified Release Preparation Not Licensed For Use In Children. 

Prophylaxis Of Cluster Headache: 

  • Adult: 240-960 Mg Daily In 3-4 Divided Doses 

Prophylaxis After Myocardial Infarction Where Beta-blockers Not Appropriate: 

  • Adult: 360 Mg Daily In Divided Doses, Started At Least 1 Week After Infarction, Given As Either 240mg Sr Tab In The Morning And 120mg In The Evening Or 120mg 3 Times Daily

Content

  • Inj: Per ml: Verapamil Hci 2.5mg; 2 ml Amp, 5 ml Amp.
  • Tab 40mg /80mg /120mg /200mg: Verapamil Hci 40mg /80mg /120mg /200mg.
  • Tab 240mg: Verapamil Hci 240mg; Sustained Release.

Pregnancy

Consult with Doctor Or Caution Advised

Stability

  • Calcium-channel Blockers

Contra Indications

  • Acute Porphyrias, Second- And Third-degree Av Block, Sick Sinus Syndrome, Sino-atrial Block, Atrial Flutter Or Fibrillation Associated With Accessory Conductingpathways (e.g. Wolff-parkinson-white-syndrome), Bradycardia, Cardiogenic Shock, History Of Heart Failure (even If Controlled By Therapy), History Of Significantly Impaired Left Ventricular Function (even If Controlled By Therapy), hypotension,

Precautions

  • Acute Porphyrias, Second- And Third-degree Av Block, Sick Sinus Syndrome, Sino-atrial Block, Atrial Flutter Or Fibrillation Associated With Accessory Conductingpathways (e.g. Wolff-parkinson-white-syndrome), Bradycardia, Cardiogenic Shock, History Of Heart Failure (even If Controlled By Therapy), History Of Significantly Impaired Left Ventricular Function (even If Controlled By Therapy), hypotension,

Lactation

  • Consult with Doctor Or Caution Advised

Side Effects

  • Constipation
  • Ankle Oedema
  • Dizziness
  • Fatigue
  • Flushing
  • Headache
  • Nausea
  • Vomiting
  • Allergic Reactions
  • Angioedema
  • Arthralgia
  • Asystole
  • Bradycardia
  • Erythema
  • Erythromelalgia
  • Gingival Hyperplasia After Long-term Treatment
  • Gynaecomastia After Long-term Treatment
  • Heart Block
  • Heart Failure
  • Hypotension
  • Increased Prolactin Concentration
  • Myalgia
  • Paraesthesia
  • Pruritus
  • Stevens-johnson Syndrome
  • Urticaria