Isoptin
Generic Name
Verapamil HCl
Packs Price
- Inj 2.5 mg(005407): 5 Ampx2 ml: 84.09: 98.93
- Tab 80 mg(021593): 5x10: 110.76: 130.30
- Tab SR 240 mg(021594): 10: 59.36: 69.84
Company
Abbott
Therapeutic Group
Calcium Channel Blockers
Indication Dosage
Treatment Of Supraventricular Arrhythmias:
- Adult: 40-120 Mg 3 Times A Day
By Slow IV Inj:
- Adult: 5-10 Mg, Given Over 2 Minutes, Preferably With ECG Monitoring
- Elderly: 5-10 Mg, To Be Given Over 3 Minutes, Preferably With ECG Monitoring
- Children 1-18 Yrs: 100-300 Mcg/kg (max 5 Mg) As A Single Dose, IV Injection Over 2-3 Minutes; Repeated After 30 Minutes If Necessary.
Paroxysmal Tachyarrhythmias:
By Slow IV Inj:
- Adult: Initially 5-10 Mg, Followed By 5 Mg After 5-10 Minutes If Required, To Be Given Over 2 Minutes, Preferably With ECG Monitoring
- Elderly: Initially 5-10 Mg, Followed By 5 Mg After 5-10 Minutes If Required, To Be Given Over 3 Minutes, Preferably With ECG Monitoring
Angina:
- Adult: 80-120 Mg 3 Times A Day
Hypertension:
- Adult: 240-480 Mg Daily In 2-3 Divided Doses
- Children 1-2 Yrs: 20 Mg 2-3 Times Daily;
- 2-18 Yrs: 40-120 Mg 2-3 Times Daily. Modified Release Preparation Not Licensed For Use In Children.
Prophylaxis Of Cluster Headache:
- Adult: 240-960 Mg Daily In 3-4 Divided Doses
Prophylaxis After Myocardial Infarction Where Beta-blockers Not Appropriate:
- Adult: 360 Mg Daily In Divided Doses, Started At Least 1 Week After Infarction, Given As Either 240mg Sr Tab In The Morning And 120mg In The Evening Or 120mg 3 Times Daily
Content
- Inj: Per ml: Verapamil Hci 2.5mg; 2 ml Amp, 5 ml Amp.
- Tab 40mg /80mg /120mg /200mg: Verapamil Hci 40mg /80mg /120mg /200mg.
- Tab 240mg: Verapamil Hci 240mg; Sustained Release.
Pregnancy
Consult with Doctor Or Caution Advised
Stability
Contra Indications
- Acute Porphyrias, Second- And Third-degree Av Block, Sick Sinus Syndrome, Sino-atrial Block, Atrial Flutter Or Fibrillation Associated With Accessory Conductingpathways (e.g. Wolff-parkinson-white-syndrome), Bradycardia, Cardiogenic Shock, History Of Heart Failure (even If Controlled By Therapy), History Of Significantly Impaired Left Ventricular Function (even If Controlled By Therapy), hypotension,
Precautions
- Acute Porphyrias, Second- And Third-degree Av Block, Sick Sinus Syndrome, Sino-atrial Block, Atrial Flutter Or Fibrillation Associated With Accessory Conductingpathways (e.g. Wolff-parkinson-white-syndrome), Bradycardia, Cardiogenic Shock, History Of Heart Failure (even If Controlled By Therapy), History Of Significantly Impaired Left Ventricular Function (even If Controlled By Therapy), hypotension,
Lactation
- Consult with Doctor Or Caution Advised
Side Effects
- Constipation
- Ankle Oedema
- Dizziness
- Fatigue
- Flushing
- Headache
- Nausea
- Vomiting
- Allergic Reactions
- Angioedema
- Arthralgia
- Asystole
- Bradycardia
- Erythema
- Erythromelalgia
- Gingival Hyperplasia After Long-term Treatment
- Gynaecomastia After Long-term Treatment
- Heart Block
- Heart Failure
- Hypotension
- Increased Prolactin Concentration
- Myalgia
- Paraesthesia
- Pruritus
- Stevens-johnson Syndrome
- Urticaria