Actemra
Generic Name
Tocilizumab
Packs Price
- Inf 80 mg/4ml (083134): 1 Vial x 4 ml: 10159.20: 11952.00
- Inf 200 mg/10ml (083135): 1 Vial x 10 ml: 25399.70: 29882.00
- Inf 400 mg/20ml (083136): 1 Vial x 20 ml: 50799.40: 59764.00
- Inf SC 162 mg/0.9ml: 1vial: 17750.55: 20883.00
- Inf SC 162 mg/0.9ml: 4vial: 65321.65: 7684900
Company
Roche
Therapeutic Group
Immunosuppressants
Indication Dosage
Moderate To Severe Active Rheumatoid Arthritis Alone Or With Methotrexate If Other Dmard Or Tnf Inhibitor Has Been Inadequate, Or In Patients Intolerant Of These Drugs:
By IV Infusion:
- Adult: 8 Mg/kg Every 4 Wks (max. Per Dose 800 Mg), For Dose Adjustments In Patients With Liver Enzyme Abnormalities, Or Low Absolute Neutrophil Or Platelet Count, Consult Product Literature
Content
- Inf: 4ml, 10 ml, 20 ml: Per ml: Tocilizumab 20mg
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
- Immunosuppressants
- Interleukin Inhibitors
Contra Indications
- Severe Active Infection, Absolute Neutrophil Count Less Than 2x109/litre
Precautions
- Severe Active Infection, Absolute Neutrophil Count Less Than 2x109/litre
Lactation
- Avoid During Treatment and for up to 20 Weeks After Discontinuing Treatment
Side Effects
- Headache
- Dizziness
- Abdominal Pain
- Antibody Formation
- Gastritis
- Gastric Ulcer
- Gi Perforation
- Hypercholesterolaemia
- Hypersensitivity
- Hypertension
- Infection
- Leucopenia
- Mouth Ulceration
- Neutropenia
- Peripheral Oedema
- Pruritus
- Raised Hepatic Transaminases
- Rash
- Upper Respiratory-tract Infection
- Anaphylaxis.
- Rare: Hypertriglyceridaemia
- Hypothyroidism
- Infusion Related Reactions
- Nephrolithiasis
- Thrombocytopenia
