Biroxime
Generic Name
Cefuroxime
Packs Price
- Inj 250 mg(047881): 5 Vial: 119.00: 140.00
- Inj 750 mg(047882): 1 Vial: 85.00: 100.00
Company
Wise
Therapeutic Group
Other Beta-Lactam, Cephalosporins & Penems
Indication Dosage
Susceptible Infections Due To Gram-positive And Gram-negative Bacteria, Upper & Lower Respiratory Tract Infection:
Oral:
- Adult: 250 Mg Twice Daily, Dose May Be Doubled In severe Lower Respiratory-tract Infections Or Ifpneumonia Is Suspected
- Children 3 Months - 1 Year: 10 Mg/kg Twice Daily (max. Per Dose 125 Mg); 2-11 Years: 15 Mg/kg Twice Daily (max. Per Dose 250 Mg);
- Child 12-17 Years: 250 Mg Twice Daily, Dose May Bedoubled In Severe Lower Respiratory-tract Infections Orif Pneumonia Is Suspected
By IV Infusion, Or IV Inj, OrIM Inj:
- Adult: 750 Mg Every 6-8 Hours; Increased If Necessary up To 1.5 G Every 6-8 Hours, For Severe Infections And Cystic Fibrosis
- Children: 20 Mg/kg Every 8 Hours (max. Per Dose 750 Mg); Increased To 50-60 Mg/kg Every 6-8 Hours (max. Perdose 1.5 G), For Severe Infection and Cystic Fibrosis
Septicaemia, Meningitis:
By IV Inj :
- Adults: 1.5 Gm Every 6 Hr. Max: 3 Gm Every 8 Hr.
- Children: 100-200 Mg/kg/day Divided Every 6-8 Hr; Max: 4.5 Gm/day Lyme Disease:
Oral:
- Adult: 500 Mg Twice Daily For 14-21 Days (for 28 Days In Lyme Arthritis)
Lower Urinary-tract Infection:
Oral:
- Adult & Children Above 12 Years: 125 Mg Twice Daily
Pyelonephritis, Pharyngitis, Tonsillitis:
Oral:
- Adult: 250 Mg Twice Daily
- Children 3 Months-12 Yrs: 125 Mg Every 12 Hr For 10 Days Or 10 Mg/kg Every 12 Hr For 10 Days; Max: 500 Mg/day
Sinusitis, Otitis Media:
- Children 3 Mth-12 Yr: 250 Mg Every 12 Hr For 10days Or 15 Mg/kg Every 12 Hr For 10 days; Max: 1 Gm/day
Surgical Prophylaxis:
By IV Inj:
- Adult: 1.5 G, To Be Administered Up To 30 Minutes Before The Procedure, Then (by IV Injection Or By IM Injection) 750 Mg Every 8 Hours If Required For Up To 3 Doses (in High-Risk Procedures)
Bone Infection, Open Fractures, Prophylaxis:
By IV Infusion, Or IV, Or IM Inj:
- Adult: 1.5 G Every 8 Hours Until Soft Tissue Closure (maximum Duration 72 Hours)
- Children 3 Months: 50 Mg/kg Every 8 Hr. Max: 4.5 Gm/day.
Content
- Cap 250mg /500mg: Cefuroxime (as Cefuroxime Axetil) 250mg /500mg.
- Tab 125mg /250mg /500mg: Cefuroxime (as Cefuroxime Axetil) 125mg /250mg /500mg.
- Susp 125mg /250mg: Per 5 ml: Cefuroxime 125mg /250mg.
Pregnancy
Caution Advised
Stability
- Cephalosporin Antibiotics
Contra Indications
Precautions
Lactation
Side Effects
- Abdominal Discomfort
- Agranulocytosis
- Allergic Reactions
- Anaphylaxis
- Aplastic Anaemia
- Blood Disorders
- Confusion
- Disturbances In Liver Enzymes
- Dizziness
- Eosinophilia
- Haemolytic Anaemia
- Hallucinations
- Headache
- Hypertonia
- Leucopenia
- Nervousness
- Pruritus
- Rashes
- Fever And Arthralgia
- Sleep Disturbances
- Urticaria
- Gi Disturbances
- Rare: Stevens-johnson Syndrome
- Thrombocytopenia
- Toxic Epidermal Necrolysis
- Transient Cholestatic Jaundice
- Transient Hepatitis