Cynfo
Generic Name
Fosfomycin
Packs Price
- Cap 500 mg: 10: 140.00: 165.46
- Susp 250 mg: 60 ml: 122.94 144.63
Company
SAMI
Therapeutic Group
Other Anti-Bacterial
Indication Dosage
Acute Uncomplicated Lower Urinary-tract Infections:
Oral Sachet:
- Adult: 3 G Single-dose 1 Sachet, Mix With 3-4 Oz Of Water. Prophylaxis Of Urinary-tract
Infections In Transurethral Surgical Procedures:
Oral Sachet:
- Adult: 3 G Single-dose 1 Sachet, Mix With 3-4 Oz Of Water, To Be Given 3 Hours Before Surgery. Dose Maybe Repeated Once, 24 Hours After Surgery
Osteomyelitis, Hospital-acquired Lower Respiratory-tract Infections When First-line Treatments Are Inappropriate Or Ineffective:
Oral:
- Adults: 500 Mg 6 Hourly.
- Children: 250 Mg 6 Hourly
By IM Inj:
- Adult: 1 G 8 Hourly;
- Children: 500 Mg 8 Hourly
By IV Infusion:
- Adult: 12-24 G Daily In 2-3 Divided Doses (max. Per Dose 8 G), Use The High-dose Regimen In Severe Infection Suspected Or Known To Be Caused By Less Sensitive Organisms
- Children: Half The Adult Dose; See Literature
Complicated Urinary-tract Infections When First-line Treatment Ineffective Or Inappropriate:
Oral:
- Adults: 500 Mg 6 Hourly.
- Children: 250 Mg 6 Hourly
By IM Inj:
- Adult: 1 G 8 Hourly;
- Children: 500 Mg 8 Hourly
By IV Infusion:
- Adult: 12-16 G Daily In 2-3 Divided Doses (max. Per Dose 8 G)
- Children: Half The Adult Dose; See Literature
Bacterial Meningitis When First-line Treatment Ineffective Or Inappropriate:
Oral:
- Adults: 500 Mg 6 Hourly.
- Children: 250 Mg 6 Hourly
By IM Inj:
- Adult: 1 G 8 Hourly;
- Children: 500 Mg 8 Hourly
By IV Infusion:
- Adult: 16-24 G Daily In 3-4 Divided Doses (max. Per Dose 8 G), Use The High-dose Regimen In Severe Infection Suspected Or Known To Be Caused By Less Sensitive Organisms
- Children: Half The Adult Dose; See Literature
Content
- Cap 500mg: Fosfomycin 500mg.
- Inj1gm IM /IV: Fosfomycin 1gm.
- Susp 250mg /500mg: Per 5 ml: Fosfomycin 250mg /500mg.
- Powder: Fosfomycin Trometamol 3gm.
Pregnancy
Use Only If Potential Benefit Outweighs Risk.
Stability
Contra Indications
Precautions
Lactation
Side Effects
- Gi Disturbances
- Diarrhoea
- Nausea
- Rash
- Vomiting
- Abdominal Pain
- Antibiotic-associated Colitis
- Dizziness
- Headache
- Decreased Appetite
- Dyspnea
- Fatigue
- Hypernatraemia
- Hypokalaemia
- Taste Disturbances
- Vertigo.
- Rare: Aplastic Anaemia
- Blood Disorders
- Eosinophilia
- Bronchospasm
- Confusion
- Hepatitis
- Jaundice
- Tachycardia