Generic Name
EtanerceptPacks Price
- Inj 50 mg: 4 PFS: 112897.57: 132820.67
Enbrel
Therapeutic Group
Anti-inflammatory And Anti-rheumatic ProductsIndication Dosage
Alone Or In Combination With Methotrexate To Treat; Severe And Progressive Rheumatoid Arthritis, Active Polyarticular-course Juvenile Idiopathic Arthritis, Active And Progressive Psoriatic Arthritis, Refractory To Puva Or Dmards Including Methotrexate, Severe Active Anylosingspondylitis:
By Sc Inj:
- Adults: 25 Mg Twice Weekly Or 50 Mg Once Weekly
- Children 4-18 Yr: 0.4 Mg/kg Twice Weekly Dose Interval Should Be 3-4 Days; Max 25 Mg Per Dose.
Chronic Severe Plaque Psoriasis Where Other Therapies Are Inappropriate:
By Sc Inj:
- Adults: 25 Mg Twice Weekly Or 50 Mg Once Weekly. Alternatively, 50 Mg Twice Weekly For Up To 12 Weeks Then, If Necessary, 25 Mg Twice Weekly Or 50 Mg Once Weekly. Continue Treatment Until Remission; Max Up To 24 Weeks Unless Longer Treatment Is Appropriate. Discontinue If No Response After 12 Weeks. Re-treatment, 25 Mg Twice Weeklyor 50 Mg Once Weekly For Up To 24 Weeks
- Children 8-18 Yrs: 0.8 Mg/kg (up To Max 50 Mg) Once Weekly For Up To 24 Weeks; Discontinue If No Response After 12 Weeks; Re-treatment, 0.8 Mg/kg (up To Max 50 Mg) Once Weekly For Up To 24 Wk.
Content
- Inj 25mg /50mg: Etanercept 25mg /50mg; Pre-Filled Syringe.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Cytokine Modulator
Contra Indications
- Sepsis Or Risk Of Sepsis, Active Infection, Active Or Recurrent Gi Bleeding Or Ulceration, Cerebrovascular Disease, History Of Gi Bleeding Or Gi Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage, Ischaemic Heart Disease, Heart Failure, Peripheral Arterial Disease, Moderate To Severe Renal Impairment Ensure Adequate Contraception.
Precautions
- Sepsis Or Risk Of Sepsis, Active Infection, Active Or Recurrent Gi Bleeding Or Ulceration, Cerebrovascular Disease, History Of Gi Bleeding Or Gi Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage, Ischaemic Heart Disease, Heart Failure, Peripheral Arterial Disease, Moderate To Severe Renal Impairment Ensure Adequate Contraception.
Lactation
- Contraindicated or Not Recommended.
Side Effects
- Injection Site Reactions
- Infection
- Headache
- Ab-dominal Pain
- Gi Disturbance
- Pruritus
- Fever
- Allergic Reactions; If Serious
- Discontinue Immediately
- Reports Of Malignancies
- Cardiovascular Symptoms
- Cholecystitis
- Pancreatitis
- Gi Haemorrhage
- Bursitis
- Depression
- Dyspnoea
- Seizures
- Angioedema
- Interstitial Lung Disease
- Cns Demyelinating Disorders Including Multiple Sclerosis And Optic Neuritis
- Pancy-topenia
- Aplastic Anaemia
- Serious Skin Reactions
Available Brands
Author
Shahid Arif