Epler
Generic Name
Eplerenone
Packs Price
- Tab 50 mg (055707): 10:595.00 :700.00
Company
Platinum
Therapeutic Group
Diuretic
Indication Dosage
Eplerenone is a medication primarily indicated for the treatment of high blood pressure (hypertension). It is also used to reduce the risk of cardiovascular events in patients who have heart failure with reduced ejection fraction (a condition where the heart's pumping ability is impaired). Eplerenone works by blocking the action of aldosterone, a hormone that can cause sodium and water retention, ultimately helping to lower blood pressure and improve heart function.
Adjunct In Stable Patients With Left Ventricular Ejection Fraction 40% Or Less With Evidence Of Heart Failure Following myocardial Infarction (start Therapy Within 3-14 Days Of Event), Adjunct In Chronic Mild Heart Failure With Leftventricular Ejection Fraction 30% Or Less:
- Adult: Initially 25 Mg Daily, Then Increased To 50 Mg Daily, Increased Within 4 Weeks Of Initial Treatment
- Children: Not Recommended.
Content
- Tab 25mg /50mg: Eplerenone (hcl) 25mg /50mg.
Pregnancy
Risk Cannot Be Ruled Out.
Stability
- Potassium-sparing Diuretics-aldosterone Antagonists
Contra Indications
- Concomitant Use Of Potassium-sparing Diuretics Or Potassium Supplements, Hyperkalaemia, Severe Hepatic Impairment.
Precautions
- Concomitant Use Of Potassium-sparing Diuretics Or Potassium Supplements, Hyperkalaemia, Severe Hepatic Impairment.
Lactation
- Caution Advised or Effect Undetermined.
Side Effects
- Azotaemia
- Constipation
- Cough
- Diarrhoea
- Dizziness
- Hyperkalaemia
- Hypotension
- Muscle Spasm
- Musculoskeletal Pain
- nausea
- pruritus
- Renal Impairment
- Syncope
- Flatulence
- Vomiting
- Rash
- Atrial Fibrillation
- Postural Hypotension
- Arterial Thrombosis
- Dyslipidaemia
- Pharyngitis
- Headache
- Insomnia
- Gynaecomastia
- Pyelonephritis
- Hyponatraemia
- Dehydration
- Eosinophilia
- Asthenia
- Malaise
- Leg Cramps
- Sweating And Pruritus.