Therapeutic Group

Indication Dosage

Pantoprazole is a medication that belongs to the class of proton pump inhibitors (PPIs). It is used to treat conditions related to excessive acid production in the stomach such as gastroesophageal reflux disease (GERD), stomach and intestinal ulcers, and Zollinger-Ellison syndrome. Pantoprazole works by reducing the amount of acid produced in the stomach, thus relieving symptoms like heartburn, difficulty swallowing, and persistent cough. It is usually taken orally, and the dosage and duration of treatment depend on the specific condition being treated.

Helicobacter Pylori Eradication: 

• Adult: 40 Mg Twice Daily, In Combination With Amoxicillin And Clarithromycin; Or In Combination With Clarithromycin And Metronidazole. 

Benign Gastric Ulcer: 

Oral: 

• Adult: 40 Mg Daily For 8 Weeks; Increased If Necessary Up To 80 Mg Daily, Dose Increased In Severe Cases 

By IV Inj, Or By IV Infusion: 

• Adult: 40 Mg Daily Until Oral Administration Can Be Resumed, Injection To Be Given Over At Least 2 Minutes 

Benign Duodenal Ulcer: 

Oral: 

• Adult: 40 Mg Daily For 4 Weeks; Increased If Necessary Up To 80 Mg Daily, Dose Increased In Severe Cases 

By IV Inj, Or By IV Infusion: 

• Adult: 40 Mg Daily Until Oral Administration Can Be Resumed, Injection To Be Given Over At Least 2 Minutes Adult: 20 Mg Daily 

Gastro-Oesophageal Reflux Disease: 

Oral: 

• Adult: 20-80 Mg Daily For 4 Weeks, Continued For Further 4 Weeks If Not Fully Healed, Dose To Be Taken In The Morning; Maintenance 20 Mg Daily And Increased To 40 Mg Daily, Increased Only If Symptoms Return 

By IV Inj, Or By IV Infusion: 

• Adult: 40 Mg Daily Until Oral Administration Can Be Resumed, Injection To Be Given Over At Least 2 Minutes 

Zollinger-Ellison Syndrome (and Other Hypersecretory Conditions): 

Oral: 

• Adult: Initially 80 Mg Daily (max. Per Dose 80 Mg), Adjusted According To Response.
• Elderly: 40 Mg Daily 

By IV Inj, Or By IV Infusion: 

• Adult: Initially 80 Mg, Alternatively 160 Mg In 2 Divided Doses, If Rapid Acid Control Required, Then 80 Mg Once Daily (max. Per Dose 80 Mg), Adjusted According To Response 

Control Of Recurring Symptoms In Healed Reflux Disease: 

• Adult: 20 Mg Once Daily When Required. 

Triple Therapy Against H. Pylori: 

• Adult: 40 Mg Twice Daily With Either Clarithromycin 250 Mg And Metronidazole 400 Mg Both Twice Daily For One Week Or Clarithromycin 500mg And Amoxicillin 1gm Both Twice Daily For One Week. 
• Children: Not Recommended.

Content

Pregnancy

Avoid Unless Potential Benefit Outweighs Risk

Stability

Contra Indications

Precautions

Lactation

Side Effects