Generic Name
HydralazinePacks Price
- Inj20 mg(042157): 1 Am: 21.25: 25.00
- Tab 25 mg(042156): 20: 58.65:69.00
Hydralazine
Therapeutic Group
Cardiac TherapyIndication Dosage
Hydralazine is a medication primarily prescribed to treat high blood pressure (hypertension). It works by relaxing and dilating blood vessels, which helps to reduce blood pressure and improve blood flow, thereby reducing the workload on the heart. Hydralazine may also be used in combination with other medications to manage certain heart conditions, such as congestive heart failure.
Moderate To Severe Hypertension (adjunct)
Oral:
- Adult: Initially 25 Mg Twice Daily, Increased If Necessary up To 50 Mg Twice Daily
Heart Failure (with Long-Acting Nitrate):
Oral:
- Adult: Initially 25 Mg 3-4 Times A Day, Subsequent Doses To Be Increased Every 2 Days If Necessary; Usual Maintenance 50-75 Mg 4 Times A Day
Hypertensive Emergencies (including During Pregnancy), Hypertension With Renal Complications:
By IV Infusion:
- Adult: Initially 200-300 Mcg/min; Usual Maintenance 50-150 Mcg/min
By Slow IV Inj:
- Adult: 5-10 Mg, To Be Diluted With 10ml Sodium Chloride 0.9%; Dose May Be Repeated After 20-30 Minutes
- Children: As Prescribed By Pediatric Physician.
Content
- Inj: Hydralazine Hcl: 120mg; Powder For Reconstitution.
- Tab: Hydralazine Hci 25mg.
Pregnancy
Caution Advised, Neonatal Thrombocytopenia Reported.
Stability
- Antihypertensive: Vasodilator
Contra Indications
- Idiopathic Systemic Lupus Erythematosus, Severe Tachycardia, High Output Heart Failure, Myocardial Insufficiency Due To Mechanical Obstruction, Corpulmonale, Dissecting Aortic Aneurysm, Acute Porphyria.
Precautions
- Idiopathic Systemic Lupus Erythematosus, Severe Tachycardia, High Output Heart Failure, Myocardial Insufficiency Due To Mechanical Obstruction, Corpulmonale, Dissecting Aortic Aneurysm, Acute Porphyria.
Lactation
- Caution Advised or Effect Undetermined.
Side Effects
- Tachycardia
- Palpitation
- Flushing
- Hypotension
- Fluid Retention
- Gastro-intestinal Disturbances; Headache
- Dizziness; Systemic Lupus Erythematosus-like Syndrome After Long-term Therapy With Over 100 Mg Daily
- Rarely Rashes
- Fever
- Peripheral Neuritis
- Polyneuritis
- Pathesthatla
- Arthralgia
- Myalgia
- Increased Lacrimation
- Nasal Congestion
- Dyspnoea
- Agitation
- Anxiety
- Anorexia; Blood Disorders (including Leucopenia
- Thrombocytopenia
- Haemolyticanae-mia)
- Abnormal Liver Function
- Jaundice
- Raised Plasma Creatinine
- Proteinuria And Haematuria Reported. Side Effects Are Less If The Dose Is Kept Below 100mg Daily.
Author
Shahid Arif