Imuran
Generic Name
Azathioprine
Packs Price
- Tab 50 mg(010058): 10x10: 1462.48: 1720.56
Company
GSK
Therapeutic Group
Immunosuppressants
Indication Dosage
Severe Acute Crohn's Disease, Maintenance Of Remission Of Crohn's Disease, Maintenance Of Remission Of Acute Ulcerative Colitis:
- Adult: 2-2.5 Mg/kg Daily, Some Patients May Respond To Lower Doses
Rheumatoid Arthritis, Severe Systemic Lupus Erythematosus And Other Connective Tissue Disorders, Polymyositis:
- Adult: Initially Up To 2.5 Mg/kg Daily In Divided Doses, Adjusted According To Response, Rarely More Than 3 Mg/kg Daily; Maintenance 1-3 Mg/kg Daily, Discontinue If No Improvement Within 3 Months
Autoimmune Conditions:
- Adult: 1-3 Mg/kg Daily, Adjusted According To Response, Discontinue If No Improvement Within3 Months
Suppression Of Transplant Rejection:
- Adult: 1-2.5 Mg/kg Daily, Adjusted According To Response
Severe Refractory Eczema:
- Adult: 1-3 Mg/kg Daily (with Normal Or High Tpmt Activity), 0.5-1.5 Mg/kg Daily (with Intermediate Tpmt Activity)
Generalized Myasthenia Gravis:
- Adult: Initially 0.5-1 Mg/kg Daily, Then Increased To 2-2.5 Mg/kg Daily, Dose Is Increased Over 3-4 Weeks,
Content
- Tab 50mg: Azathioprine 50mg.
Pregnancy
Consult with Doctor Or Caution Advised
Stability
- Cytotoxic Immunosuppressant
- Antimetabolites
Contra Indications
- Biliary Stasis, Toxic Hepatitis, Absent Or Very Low Thiopurine Methyltransferase (tpmt) Activity
Precautions
- Biliary Stasis, Toxic Hepatitis, Absent Or Very Low Thiopurine Methyltransferase (tpmt) Activity
Lactation
- Consult with Doctor Or Caution Advised
Side Effects
- Arthralgia
- Cholestatic Jaundice
- Diarrhoea
- Dizziness
- Dose-related Bone Marrow Suppression
- Fever
- Hair Loss
- Herpes Zoster Infection
- Hypersensitivity Reactions
- Hypotension
- Interstitial Nephritis
- Liver Impairment
- Malaise
- Myalgia
- Nausea
- Neutropenia
- Rash
- Rigors
- Thrombocytopenia
- Vomiting.
- Rare: Hepatic Veno-occlusive Disease
- Lymphoma
- Pancreatitis
- Pneumonitis
- Red Cell Aplasia