Labetalol
Generic Name
Labetalol Hcl
Packs Price
- Tab 100 mg(042154): 20: 148.12 125.90
- Inj 50 mg(042155): 1 Vialx10 ml: 21.25: 25.00
Company
Zafa
Therapeutic Group
Beta Blocking Agent
Indication Dosage
Controlled Hypotension In Anaesthesia:
By IV Infusion, Or By IV Inj:
- Adult: Consult Product Literature.
Hypertension Of Pregnancy:
By IV Infusion:
- Adult: Initially 20 Mg/hour, Then Increased If Necessary To 40 Mg/hour After 30 Minutes, Then Increased If Necessary To 80 Mg/hour After 30 Minutes, Then Increased If Necessary To 160 Mg/hour After 30 Minutes, Adjusted According To Response; Usual Maximum 160 Mg/hour
Oral:
- Adult: Use Dose For Hypertension
Hypertension Following Myocardial Infarction:
By IV Infusion:
Adult: 15 Mg/hour, Then Increased To Up To120 Mg/hour, Dose To Be Increased Gradually
Hypertensive Emergencies:
By IV Inj:
- Adult: 50 Mg, Given Over At Least 1 Minute, Then 50 Mg Every 5 Minutes If Required Until A Satisfactory Response Occurs; Maximum 200 Mg Per Course
By IV Infusion:
- Adult: Initially 2 Mg/minute Until A Satisfactory Response Is Achieved, Then Discontinue; Usual Dose 50-200 Mg
Hypertension:
- Adult: Initially 100 Mg Twice Daily, Increased At Intervals Of 14 Days; Usual Dose 200 Mg Twice Daily, Increased If Necessary Up To 800 Mg Daily In 2 Divided Doses, To Be Taken With Food, Higher Doses To Be Given In 3-4 Divided Doses; Max 2.4 G Per Day
- Elderly: Initially 50 Mg Twice Daily, Increased At Intervals Of 14 Days; Usual Dose 200 Mg Twice Daily, Increased If Necessary Up To 800 Mg Daily In 2 Divided Doses, To Be Taken With Food, Higher Doses To Be Given In 3-4 Divided Doses; Max 2.4 G Per Day
By IV Inj:
- Adult: 50 Mg, Dose To Be Given Over At Least 1 Minute, Then 50 Mg After 5 Minutes If Required; Maximum 200 Mg Per Course
By IV Infusion:
- Adult: Initially 2 Mg/minute Until A Satisfactory Response Is Achieved, Then Discontinue; Usual Dose50-200 Mg
- Children: Not Recommended.
Content
- Inj: Per ml: Labetalol Hci 5mg; 10 ml (50mg), 20 ml (100mg) Amp.
- Tab 100mg /200mg: Labetalol Hci 100mg /200mg.
Pregnancy
Avoid, Known To Be Harmful, Except Possibly In The First Trimester
Stability
Contra Indications
- 2nd Or 3rd Degree Av Block (without Pacemaker, Severe Bradycardia, Sick Sinus Syndrome, Un-controlled Heart Failure, Cardiogenic Shock, Severe Peripheral Arterial Disease, Hypotension, Metabolic Acidosis, Untreated Pheochromocytoma, Severe Asthma Or Copd.
Precautions
- 2nd Or 3rd Degree Av Block (without Pacemaker, Severe Bradycardia, Sick Sinus Syndrome, Un-controlled Heart Failure, Cardiogenic Shock, Severe Peripheral Arterial Disease, Hypotension, Metabolic Acidosis, Untreated Pheochromocytoma, Severe Asthma Or Copd.
Lactation
- Caution Advised; Risk of Possible Toxicity.
Side Effects
- Cardiovascular Effects Including Bradycardia
- Altered Blood Sugar
- hematology And Lipid Levels
- Difficulty In Micturition
- Epigastric Pain
- Liver Damage
- Nausea
- Postural Hypotension
- Vomiting
- Weakness. Rare Lichenoid Rash