Lorelin
Generic Name
Leuprorelin Acetate
Packs Price
- Depot Inj 11.25 mg(053846): 1: 17850.00: 21000.00
- Depot Inj 3.75mg: 1: 6875.65: 8089.00
- Depot Inj 7.5mg: 1: 12750.00: 15000.00
Company
Medisure
Therapeutic Group
Pituitary And Hypothalamic Hormones And Analogues
Indication Dosage
Advanced Prostate Cancer As An Alternative To Surgical Castration, Adjuvant Treatment To Radiotherapy Or Radical Prostatectomy In Advanced Prostate Cancer, Metastatic Prostate Cancer:
By Sc Inj:
- Adult: 11.25 Mg Every 3 Months Or;
By Sc Or IM Inj:
- Adult: 3.75 Mg Every Month
Endometriosis:
By IM Inj:
- Adult: Initially 11.25 Mg For 1 Dose As A Single Dose In the First 5 Days Of the Menstrual Cycle, Then 11.25 Mg Every 3 Months For a Maximum of 6 Months(course Not To Be Repeated) Or;
By Sc Or IM Inj:
- Adult: Initially 3.75 Mg For 1 Dose As A Single Dose In the First 5 Days Of the Menstrual Cycle, Then 3.75 Mg Every Month For a Maximum of 6 Months (course Not To Be Repeated)
Endometrial Thinning Before Intra-uterine Surgery:
By Sc Or IM Inj:
- Adult: Initially 3.75 Mg For 1 Dose As A Single Dose Between Days 3 And 5 Of the Menstrual Cycle,5-6 Weeks Before Surgery
Reduction Of Size Of Uterine Fibroids And Of Associated Bleeding Before Surgery:
By Sc Or IM Inj:
- Adult: Initially 3.75 Mg Every Month Usually For 3-4 Months (maximum 6 Months)
Content
- Inj 3.75mg /5mg /7.5mg /11.25mg /22.5mg: Le-uprorelin Acetate 3.75mg /5mg /7.5mg /11.25mg /22.5mg; Powder In Microcapsule Depot In Vial Plus 1 ml Diluent.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Gonadotrophin Releasing Hormones Analogue
Contra Indications
- Undiagnosed Vaginal Bleeding.
Precautions
- Undiagnosed Vaginal Bleeding.
Lactation
Side Effects
- Altered Glucose Tolerance And Blood Lipids
- Anaphylaxis
- Anorexia
- Asthma
- Breast Tenderness (males And Females)
- Changes In Blood Pressure
- Breast Size And Scalp And Body Hair
- Chills
- Decrease In Trabecular Bone Density
- Depression
- Diarrhoea
- Dizziness
- Dyspareunia
- Fatigue
- Fever
- Gi Disturbances
- Headache
- Hot Flushes
- Hypersensitivity Reactions
- Jaundice
- Leucopenia
- Local Reactions At Injection Site
- Loss Of Libido
- Menopausal-like Symptoms
- Migraine
- Mood Changes
- Musculoskeletal Pain And Weakness
- Nausea
- Palpitation
- Paraesthesia
- Paralysis
- Pruritus
- Pulmonary Embolism
- Rash
- Sexual Dysfunction
- Sleep Disturbances
- Spinal Fracture
- Thrombocytopenia
- Urticaria
- Vaginal Bleeding
- Vaginal Dryness
- Visual Disturbances
- Vomiting
- Weight Changes