Nelizamet
Generic Name
Rosiglitazone And Metformin
Packs Price
- Tab 1/500 mg (044608): 10: 55.25: 65.00
- Tab 2/500 mg (044609): 10: 93.50: 110.00
- Tab 4/500 mg(044610): 10: 148.75: 175.00
Company
Highnoon
Therapeutic Group
Blood Glucose Lowering Drugs, Excluding Insulin
Indication Dosage
Type 2 Diabetes Not Controlled By Metformin Alone, Or In Triple Therapy With A Sulphonylureas:
- Adult: Initially 1 Tab Of 2 Mg/1000 Mg Tab, Twice Daily With Meals Or Right After Meals. Increase To 2 Tab Of 2 Mg/500 Mg Tab Or 1 Tab Of 4 Mg/1000 Mg Tab Twice Daily After 8 weeks if Greater Glycaemic Control Is Required. As Per Requirement, This Medicine May Be Used To Substitute Concomitant Rosiglitazone And Metformin In Existing Dual Or Triple Therapy.
- Children: Not Recommended.
Content
- Tab 1 /500mg: Rosiglitazone (as Maleate) 1mg, Metformin Hydrochloride 500mg.
- Tab 2 /500mg: Rosiglitazone (as Maleate) 2mg, Metformin Hydrochloride 500mg.
- Tab 4 /500mg: Rosiglitazone (as Maleate) 4mg, Metformin Hydrochloride 500mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Biguanide
- Thiazolidinedione
Contra Indications
- Cardiac Failure Or History Of Cardiac Failure, Respiratory Failure, Recent Mi, Shock, Hepatic Impairment, Alcohol Intoxication, Alcoholism, Diabetic Ketoacidosis, Renal Impairment, Dehydration, Severe Infection, Acute Coronary Syndrome.
Precautions
- Cardiac Failure Or History Of Cardiac Failure, Respiratory Failure, Recent Mi, Shock, Hepatic Impairment, Alcohol Intoxication, Alcoholism, Diabetic Ketoacidosis, Renal Impairment, Dehydration, Severe Infection, Acute Coronary Syndrome.
Lactation
- Contraindicated or Not Recommended
Side Effects
- Disturbances In Visual Acuity
- Hepatic Impairment
- Renal Impairment
- Risk Of Fractures (especially In Women)
- Ischaemic Heart Disease
- Anaemia
- Hypoglycaemia
- Gi Upset
- Dizziness
- Weight Gain
- Oedema.