Generic Name
SorafenibPacks Price
- Tab 200 mg(052224): 6x10: 151496.93: 178231.68
Nexavar
Therapeutic Group
Anti-neoplasticsIndication Dosage
Sorafenib is a medication primarily used to treat advanced kidney cancer (renal cell carcinoma) and advanced liver cancer (hepatocellular carcinoma) in adults. It is prescribed when these cancers are at an advanced stage or cannot be surgically removed. Sorafenib works by inhibiting the growth of cancer cells and blocking the formation of blood vessels that supply nutrients to the tumor.
Treatment Of Advanced Renal Cell Carcinoma When Treatment With Interferon Alfa Or Interleukin-2 Has Failed Or Is Unsuitable, Treatment Of Progressive, Locally advanced, Or Metastatic, Differentiated Thyroid carcinoma That Is Refractory To Radioactive Iodine, Treatment Of Hepatocellular Carcinoma:
- Adult: 400 Mg Twice Daily, For Dose Adjustments Due To side Effects, Consult Product Literature
- Children: Not Recommended.
Content
- Tab 200mg: Sorafenib 200mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Protein Kinase Inhibitor
Contra Indications
- None Known
Precautions
- None Known
Lactation
- Contraindicated. Discontinue Breast-feeding
Side Effects
- Anorexia
- Arthralgia
- Asthenia
- Congestive Heart Failure
- Depression
- Dermatitis
- Desquamation
- Dysgeusia
- Dyspepsia
- Dysphagia
- Dysphonia
- Erythema
- Fatigue
- Flushing
- Gi Upset
- Gastro-oesophageal Reflux Disease
- Haemorrhage
- Hand-foot Skin Reaction
- Hyperkeratosis
- Hypertension
- Hypophosphataemia
- Hypophosphataemia
- Keratoacanthoma
- Malaise
- Muscle Spasms
- Myalgia
- Myocardial Infarction
- Myocardialischaemia
- Peripheral Neuropathy
- Proteinuria
- Pruritus
- Rash
- Renal Failure
- Rhinorrhea
- Thyroid Dysfunction
- Tinnitus
- Alopecia
- Bone-marrow Suppression
- Hyperuricaemia
- Nausea
- Oral Mucositis
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting
Available Brands
Author
Shahid Arif