Nitrofurantoin is a medication primarily indicated for the treatment and prevention of urinary tract infections (UTIs) caused by susceptible bacteria. It works by inhibiting the growth of bacteria in the urinary tract, thereby helping to alleviate the symptoms of UTIs and prevent their recurrence.
Acute Uncomplicated Urinary-tract Infections:
Adult: 50 Mg 4 Times A Day For 3-7 Days, To Be Taken With Food
Children 3 Months - 11 Yrs: 750 Micrograms/kg 4 Times A Day For 3-7 Days;
12-17 Years: 50 Mg 4 Times A Day For 3-7 Days
Severe Chronic Recurrent Urinary-tract Infections:
Adult: 100 Mg 4 Times A Day For 7 Days, To Be Taken With Food, Reduce Dose Or Discontinue Treatment If Severe Nausea Occurs
Children 12-17 Years: 100 Mg 4 Times A Day For 3-7 Days
Prophylaxis Of Urinary tract Infection (considered For Recurrent Infection, Significant urinary tract Anomalies, Or Significant Kidney Damage)
Adult: 50-100 Mg Once Daily, Dose To Be Taken At Night
Children 3 Months - 11 Yrs: 1 Mg/kg Once Daily, To Be Taken At Night; 12-17 Yrs: 50-100 Mg Once Daily, To Be Taken At Night
Genito-urinary Surgical Prophylaxis:
Adult: 100 Mg Twice Daily On the Day Of the Procedure And For 3 Days Afterwards
Content
Tab /Cap 100mg: Nitrofurantoin 100mg.
Pregnancy
Avoid At Term, May Produce Neonatal Haemolysis.
Stability
Nitrofuran
Contra Indications
Acute Porphyrias, G6pd
Deficiency, Infants Less Than 3 Months Old
Precautions
Acute Porphyrias, G6pd
Deficiency, Infants Less Than 3 Months Old
Lactation
Avoid; Small Amounts in Milk but May Be Used to Produce Haemolysis
Side Effects
Acute Pulmonary Reactions
Anaphylaxis
Angioedema
Anorexia
Chronic Pulmonary Reactions (pulmonary Fibrosis Reported; Possible Association With Lupus Erythematosus-like Syndrome)