Aliskiren is a medication primarily prescribed to manage hypertension (high blood pressure). It belongs to a class of drugs known as direct renin inhibitors and effectively works to lower blood pressure by inhibiting the activity of renin, an enzyme involved in regulating blood pressure. Aliskiren may be used alone or in combination with other antihypertensive medications when lifestyle changes alone are insufficient in controlling blood pressure.
Essential Hypertension Either Alone Or In Combination With Other Anti-hypertensives:
Adult: 150 Mg Once Daily, Increased If Necessary To 300 Mg Once Daily
Content
Tab 150mg /300mg: Aliskiren 150mg /300mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
Renin Inhibitor
Contra Indications
Concomitant Treatment With An Ace Inhibitor Or An Angiotensin-ii Receptor Antagonist In Patients With An Egfr Less Than 60 Ml/minute/1.73m2, Concomitant Treatment With An Ace Inhibitor Or An Angiotensin-ii Receptor Antagonist In Patients With Diabetes Mellitus, Hereditary Angioedema, Idiopathic Angioedema
Children: Not Recommended.
Precautions
Concomitant Treatment With An Ace Inhibitor Or An Angiotensin-ii Receptor Antagonist In Patients With An Egfr Less Than 60 Ml/minute/1.73m2, Concomitant Treatment With An Ace Inhibitor Or An Angiotensin-ii Receptor Antagonist In Patients With Diabetes Mellitus, Hereditary Angioedema, Idiopathic Angioedema
Children: Not Recommended.
Lactation
Not Recommended.
Side Effects
Arthralgia
Dizziness
Hyperkalaemia
Diarrhoea
Liver Disorders
Nausea
Vertigo
Vomiting.
Rare: Acute Renal Failure (reversible On Discontinuation Of Treatment)