Sipmit
Generic Name
Sitagliptin And Metformin
Packs Price
- Tab 50/1000 mg(084043): 14 1213.80: 1428.00
- Tab 50/500 mg(084038): 14 1201.90: 1414.00
Company
DeMont
Therapeutic Group
Blood Glucose Lowering Drugs, Excluding Insulin
Indication Dosage
Type 2 Diabetes Mellitus Not Controlled By Metformin Alone Or In Combination With Either A Sulfonylurea Or Pioglitazone Or Insulin:
- Adult: Initially 1 Tablet50mg/500 Mg Or 50 Mg/1000 Mg Twice Daily. Doses Of Sulfonylurea Or Insulin May Need To Be Reduced. Max Daily Dose Of Sitagliptin 100 Mg.
- Children: Not Recommended.
Content
- Tab 50mg /500mg: Sitagliptin (as Phosphate Monohydrate) 50mg, Metformin Hydrochloride 500mg.
- Tab 50mg /850mg: Sitagliptin (as Phosphate Monohydrate) 50mg, Metformin Hydrochloride 850mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Biguanide
- Dipeptidyl Peptidase-4 Inhibitor
Contra Indications
- Renal Or Hepatic Impairment, Diabetic Ketoacidosis Or Pre-coma, Cardiac Or Respiratory Failure, Recent Mi, Acute Alcohol Intoxication, Alcoholism.
Precautions
- Renal Or Hepatic Impairment, Diabetic Ketoacidosis Or Pre-coma, Cardiac Or Respiratory Failure, Recent Mi, Acute Alcohol Intoxication, Alcoholism.
Lactation
Side Effects
- Serious Hyper Sensitivity Reactions Including Anaphylaxis And Stevens-johnson Syndrome (discontinue)
- nausea
- Lactic Acidosis (discontinue)
- Hypoglycaemia
- Constipation
- Headache
- Diarrhoea
- Vomiting.