Generic Name
IvabradinePacks Price
- Tab 5 mg: Pack Size 14's: Rs.445
- Tab 7.5 mg: Pack Size 14's: Rs.445
Sivab
Therapeutic Group
Cardiac TherapyIndication Dosage
Ivabradine is a medication primarily indicated for the treatment of stable angina pectoris and chronic heart failure in adults. It is prescribed when beta-blockers are not suitable or well-tolerated, and it works by reducing the heart rate, thereby decreasing the workload on the heart and improving its overall efficiency. Ivabradine helps alleviate symptoms such as chest pain and shortness of breath, making it a valuable therapeutic option for individuals with these cardiovascular conditions.
Treatment Of Angina In Patients With Normal Sinus Rhythm:
- Adult: Initially 5 Mg Twice Daily For 3-4 Weeks, Then Increased If Necessary To 7.5 Mg Twice Daily; Reduced If Not Tolerated To 2.5-5 Mg Twice Daily, Heart Rate At Rest Should Not Be Allowed To Fall Below 50 Beats Per Minute
- Elderly: Initially 2.5 Mg Twice Daily, Heart Rate At Rest Should Not Be Allowed To Fall Below 50 Beats Per Minute.
Mild To Severe Chronic Heart Failure:
- Adult: Initially 5 Mg Twice Daily For 2 Weeks, Then Increased If Necessary To 7.5 Mg Twice Daily; Reduced If Not Tolerated To 2.5 Mg Twice Daily, Heart Rate At Rest Should Not Be Allowed To Fall Below 50 Beats Per Minute
- Children: Not Recommended.
Content
- Tab 5mg /7.5mg: Ivabradine (as Hci) 5mg /7.5mg.
Pregnancy
Contraindicated In Pregnancy,
Stability
- Sinus Node I Inhibitor
Contra Indications
- Cardiogenic Shock, Acute Myocardial Infarction, Congenital Qt Syndrome. Do Not Initiate For Angina If Heart Rate Below 70 Beats Per Min Or In Chronic Heart Failure Below 75 Beats Per Minute, Severe Hepatic Or Renal Impairment, Immediately After Cerebrovascular Accident, Patients Dependent On Pacemaker, Second- And Third-degree Heart Block, Severe Hypotension, Sick-sinus Syndrome, Sino-atrial Block, Unstable Angina, Unstable Or Acute Heart Failure.
Precautions
- Cardiogenic Shock, Acute Myocardial Infarction, Congenital Qt Syndrome. Do Not Initiate For Angina If Heart Rate Below 70 Beats Per Min Or In Chronic Heart Failure Below 75 Beats Per Minute, Severe Hepatic Or Renal Impairment, Immediately After Cerebrovascular Accident, Patients Dependent On Pacemaker, Second- And Third-degree Heart Block, Severe Hypotension, Sick-sinus Syndrome, Sino-atrial Block, Unstable Angina, Unstable Or Acute Heart Failure.
Lactation
- Contraindicated
Side Effects
- Atrial Fibrillation
- Visual Disturbances Blurred Vision
- Bradycardia
- Dizziness
- First-degree Heart Block
- Headache
- Phosphenes
- Ventricular Extrasystoles
- Angioedema
- Constipation
- Diarrhoea
- Dyspnea
- Eosinophilia
- Hyperuricaemia
- Muscle Cramps
- Nausea
- Palpitations
- Raised Plasma-creatinine Concentration
- Rash
- Supraventricular Extrasystoles
- Vertigo. Rare Second And Third-degree Heart Block
- Sick Sinus Syndrome
Author
Shahid Arif