Generic Name
ProchlorperazinePacks Price
- Inj12.5 mg(001233): 10 Ampx1 ml: 59.04: 69.46
- Tab 5 mg (000824): 15x20: 184.667: 217.26
Stemetil
Therapeutic Group
Anti-Emetic & Anti-NauseantsIndication Dosage
Prochlorperazine is a medication that is primarily used to treat nausea and vomiting caused by various conditions, such as migraines, chemotherapy, and gastrointestinal disorders. It belongs to a class of drugs called phenothiazines, which work by blocking certain dopamine receptors in the brain. This medication can also be used to treat certain psychiatric conditions, such as schizophrenia and anxiety, but it is not typically the first-line treatment for these disorders.
Nausea And Vomiting, Acute Attack:
Oral:
- Adult: Initially 20 Mg, Then 10 Mg After 2 Hours
By Deep IM Inj:
- Adult: 12.5 Mg As Required, Followed By An Oral Dose After 6 Hours, if Necessary.
Nausea And Vomiting, Prevention And Treatment:
Oral:
- Adult: 5-10 Mg 2-3 Times A Day.
- Children 1-11 Years (body weight 10 Kg And Above): 250 Micrograms/kg 2-3 Times A Day.
- Children 12-17 Years: 5-10 Mg Up To 3 Times A Day If Required.
By Deep IM Inj:
- Adult: 12.5 Mg As Required, Followed By An Oral Dose After 6 Hours, If Necessary.
- Children 2-4 Years: 1.25-2.5 Mg Up To 3 Times A Day If Required;
- 5-11 Years: 5-6.25 Mg Up To 3 Times A Day If Required;
- 12-17 Years: 12.5 Mg Up To 3 Times A Day If Required
Labyrinthine Disorders:
Oral:
- Adult: 5 Mg 3 Times A Day, Increased If Necessary To 30 Mg Daily In Divided Doses, Increased Gradually, Then Reduced To 5-10 Mg Daily, Dose Is Reduced After Several Wks
Nausea And Vomiting In Previously Diagnosed Migraine:
Oral:
- Adult & Children 12 Yrs: 3-6 Mg Twice Daily.
Schizophrenia And Other Psychoses, Mania:
Oral:
- Adult: 12.5 Mg Twice Daily For 7 Days, Dose To Be Adjusted At Intervals Of 4-7 Days According To Response; Usual Dose 75-100 Mg Daily.
By Deep IM Inj:
- Adult: 12.5-25 Mg 2-3 Times A Day.
Short-term Adjunctive Management Of Severe Anxiety:
Oral:
- Adult: 15-20 Mg Daily In Divided Doses; Maximum 40 Mg Per Day. Doses Are Expressed As Prochlorperazine Maleate Or Mesilate; 1mg Prochlorperazine Maleate: 1 Mg Prochlorperazine Mesilate.
Content
- Inj: Per 1 ml Amp: ProchlorPerazine Mesilate 12. 5mg.
- Tab 3mg /5mg: ProchlorPerazine Maleate 3mg /5mg.
Pregnancy
Caution Advised
Stability
- Antihistamine
Contra Indications
- Children Under 10 Kg Body Weight, Cns Depression, Comatose States, Phaeochromocytoma, Bone Marrow Depression, Liver Impairment.
Precautions
- Children Under 10 Kg Body Weight, Cns Depression, Comatose States, Phaeochromocytoma, Bone Marrow Depression, Liver Impairment.
Lactation
- Caution Advised
Side Effects
- Impaired Judgment And Dexterity
- Cns Disturbances
- Acute Dys Tonic Reactions Such As Facial And Skeletal Muscle Spasms And Oculogyric Crises
- Anticholinergic Effects
- Ecg And Endocrine Changes
- Allergic Effects And Extra-pyramidal Symptoms Occur Rarely At Low Dosage.
Available Brands
Author
Shahid Arif