Generic Name
TacrolimusPacks Price
- Cap.0.5 mg(086850): 30: 993.11: 1168.37
- Cap.1 mg(086851): 30: 1655.19: 1947.28
- Cap.5 mg(086851): 30: 298.54: 3527.69
Unigraf
Therapeutic Group
ImmunosuppressantsIndication Dosage
Prophylaxis Of Graft Rejection Following Liver Transplantation, Starting 12 Hours After Transplantation:
- Adult: Initially 100-200 Mcg/kg Daily In 2 Divided Doses
Prophylaxis Of Graft Rejection Following Kidney Transplantation, Starting Within 24 Hours Of Transplantation:
- Adult: Initially 200-300 Mcg/kg Daily In 2 Divided Doses
Prophylaxis Of Graft Rejection Following Heart Transplantation Following Antibody Induction, Starting Within 5 Days Of Transplantation:
- Adult: Initially 75 Mcg/kg Daily In 2 Divided Doses
Prophylaxis Of Graft Rejection Following Heart Transplantation Without Antibody Induction, Starting Within 12 Hours Of Transplantation:
- Adult: Initially 75 Mcg/kg Daily In 2 Divided Doses
Allograft Rejection Resistant To Conventional Immunosuppressive Therapy:
- Adult: Consult Product Literature Or Seek Specialist Advice
Content
- Cap 0.5mg /1mg /5mg: Tacrolimus 0.5mg /1mg /5mg.
Pregnancy
Consult with Doctor Or Caution Advised
Stability
- Calcineurin Inhibitor
Contra Indications
- Avoid Concurrent Administration With Ciclosporin (care If Patient Has Previously Received Ciclosporin).
Precautions
- Avoid Concurrent Administration With Ciclosporin (care If Patient Has Previously Received Ciclosporin).
Lactation
- Consult with Doctor Or Caution Advised
Side Effects
- Alopecia
- Anaemia
- Anorexia
- Anxiety
- Arthralgia
- Ascites
- Bile-duct Abnormalities
- Blood Disorders
- Cholestasis
- Convulsion
- Confusion
- Depression
- Dizziness
- Dyspnea
- Electrolyte Disturbances
- Gi Disturbance Including Dyspepsia
- Inflammatory And Ulcerative Disorders
- Haemorrhage
- Hepatic Dysfunction
- Hyperglycaemia
- Hyperkalaemia
- Hypertension
- Hyperuricaemia
- Hypokalaemia
- Impaired Hearing
- Insomnia
- Ischaemic Events
- Jaundice
- Leucopenia
- Mood Changes
- Muscle Cramp
- Oedema
- Pancytopenia
- Paraesthesia
- Parenchymal Lung Disorders
- Peripheral Neuropathy
- Photophobia
- Pleural Effusion
- Psychosis
- Renal Failure And Impairment
- Renal Tubular Necrosis
- Seizures
- Sleep Disturbances
- Sweating
- Tachycardia
- Thrombocytopenia
- Thromboembolic Events
- Tinnitus
- Tremor
- Urinary Abnormalities
- Visual Disturbances
- Weight Changes
- Amnesia
- Arrhythmia
- Cardiac Arrest
- Cardiomyopathy
- Cataract
- Cerebrovascular Accident
- Coagulation Disorders
- Coma
- Haemolytic Anaemia
- Pure Red Cell Aplasia
- Myasthenia
- Hirsutism.
- Rare: Stevens-johnson Syndrome.
Available Brands
Author
Shahid Arif