Generic Name
Domperidone And CinnarizinePacks Price
- Tab 15/20 mg: 5x10: 147.05: 173.00
Zenome
Therapeutic Group
Anti-Emetic & Anti-NauseantsIndication Dosage
The combination of Domperidone and Cinnarizine is commonly used for the treatment of nausea and vomiting associated with various conditions such as motion sickness, vertigo, and gastrointestinal disorders. Domperidone is a dopamine antagonist that increases the motility of the digestive system, while Cinnarizine is a calcium channel blocker that acts on the vestibular system to reduce motion sickness. The combination of these two drugs provides effective relief from symptoms such as nausea, vomiting, and dizziness.
Nausea, Vomiting, Vertigo, Epigastria, Sense Of Fullness, Upper Abdominal Distention, Regurgitation, And Gastro-intestinal Pain:
- Adult: 10-20 Mg 3 Times A Day, Before Meals. Max 80 Mg Daily. Re-evaluate the Need For Continued Treatment After 4 Weeks.
- Children: Not Recommended.
Content
- Syp: Per 5 ml: DomPeridone Maleate Equiv To 5mg DomPeridone, Cinnarizine 10mg
- Tab: DomPeridone Maleate 19.10mg Equiv To 15mg DomPeridone, Cinnarizine 20mg.
Pregnancy
Contraindicated
Stability
- Antidopaminergic
- Antihistamine
Contra Indications
- Cardiac Disease, When Administered Concomitantly With Drugs That Prolong The Qt Interval Or Potent Cyp3a4 Inhibitors, Hepatic Impairment, Prolactinoma, Gi Haemorrhage, Mechanical Perforation Or Obstruction.
Precautions
- Cardiac Disease, When Administered Concomitantly With Drugs That Prolong The Qt Interval Or Potent Cyp3a4 Inhibitors, Hepatic Impairment, Prolactinoma, Gi Haemorrhage, Mechanical Perforation Or Obstruction.
Lactation
- Not Recommended.
Side Effects
- Drowsiness
- Dry Mouth
- Malaise
- Anxiety
- Diarrhoea
- Galactorrhoea
- Headache
- Pruritus
- Rash
- Agitation
- Amenorrhoea
- Convulsions
- Extra-pyramidal Disorders
- Gynaecomastia
- Nervousness
- Oculogyric Crisis
- Qt-interval Prolongation
- Sudden Cardiac Death
- Urinary Retention
- Ventricular Arrhythmias
- Gi Upset
- Raised Serum Prolactin.
Available Brands
Author
Shahid Arif