Alendronate And Cholecalciferol

Therapeutic Group

Drugs For Treatment Of Bone Diseases

Indication Dosage

Treatment Of Post-menopausal Osteoporosis To Reduce Risk Of Vertebral And Hip Fractures: 

  • Adult: 1 Tab Once Weekly. 
  • Children: Not Recommended.

Content

  • OW (Once Weekly) Tab 70mg: Alendronate Sodium Equiv 70mg Alendronic Acid, Cholecalciferol 70 Mcg.

Pregnancy

Contraindicated

Stability

  • Bisphosphonate

Contra Indications

  • Renal Impairment With Gfr <35 Ml/min, Oesophageal Abnormalities, Stricture, Achalasia Or Inability To Remain Upright For 30 Min After Dosing, Hypocalcaemia.

Precautions

  • Renal Impairment With Gfr <35 Ml/min, Oesophageal Abnormalities, Stricture, Achalasia Or Inability To Remain Upright For 30 Min After Dosing, Hypocalcaemia.

Lactation

  • Contraindicated

Side Effects

  • Abdominal Distension And Pain
  • Constipation
  • Diarrhoea
  • Dyspepsia
  • Flatulence
  • Headache
  • Oesophageal Reactions (oesophagitis
  • Oesophageal Ulcers
  • Oesophageal Stricture And Oesophageal Erosions)
  • Regurgitation
  • Musculoskeletal Pain
  • Episcleritis
  • Erythema
  • Gastritis
  • Nausea
  • Rash
  • Scleritis
  • Uveitis
  • Vomiting.
  • Rare: Atypical Femoral Fractures With Long-term Use
  • Hypocalcaemia
  • Osteonecrosis Of The Jaw
  • Photosensitivity
  • Severe Skin Reactions
  • Stevens-johnson Syndrome
  • Toxic Epidermal Necrolysis
  • Upper Gastro-intestinal Ulcers