Aliskiren And Hydrochlorothiazide
Therapeutic Group
Anti-hypertensiveIndication Dosage
Aliskiren and Hydrochlorothiazide is a medication prescribed for the treatment of high blood pressure (hypertension) in adults. This combination drug works by combining the effects of Aliskiren, which inhibits the action of a hormone that raises blood pressure, and Hydrochlorothiazide, which helps the body eliminate excess salt and water, further reducing blood pressure.
Essential Hypertension:
- Adults: 1 Tab Once Daily.
- Children: Not Recommended,
Content
- Tab 300 /12.5mg: Aliskiren 300mg. Hydrochloro-thiazide 12.5mg
- Tab 300 /25mg: Aliskiren 300mg, Hydrochlorothiazide 25mg.
- Tab 150 /12.5mg: Aliskiren 150mg, Hydrochlorothiazide 12.5mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Diuretic
- Renin Inhibitor
Contra Indications
- Acute Porphyrias, Anuria, Renal Decompensation, Concomitant Treatment With An Ace Inhibitor Or An Angiotensin-ii Receptor Antagonist In Patients With An Egfr Less Than 60 Ml/minute/1.73m2,concomitant Treatment With An Ace Inhibitor Or Anangiotensin-ii Receptor Antagonist In Patients With Diabetes Mellitus, Hereditary Angioedema, Idiopathic Angioedema
Precautions
- Acute Porphyrias, Anuria, Renal Decompensation, Concomitant Treatment With An Ace Inhibitor Or An Angiotensin-ii Receptor Antagonist In Patients With An Egfr Less Than 60 Ml/minute/1.73m2,concomitant Treatment With An Ace Inhibitor Or Anangiotensin-ii Receptor Antagonist In Patients With Diabetes Mellitus, Hereditary Angioedema, Idiopathic Angioedema
Lactation
- Not Recommended.
Side Effects
- Arthralgia
- Dizziness
- Hyperkalaemia
- Diarrhoea
- Liver Disorders
- Nausea
- Vertigo
- Vomiting.
- Rare: Acute Renal Failure (reversible On Discontinuation Of Treatment)
- Hypotension
- Palpitation
- Peripheral Oedema
- Cough
- Pruritus
- Rash
- Stevens-johnson Syndrome
- Toxic Epidermal Necrolysis
- Urticaria
- Anaemia
- Angioedema
- Erythema.