Ampicillin And Cloxacillin

Therapeutic Group

Beta-Lactam Anti-bacterials, Penicillins

Indication Dosage

Respiratory Tract Infections, Ear, Nose And Throat Infections, Pelvic Infections, Urinary Tract Infections, Cystitis And Pyelonephritis, Skin And Soft Tissue Infections, GI infections, Septicaemia, Endocarditis, And Orthopaedic Infection: 

Oral: 

  • Adults: 500 Mg-1gm Every 6 hours or More Frequently According To The Severity Of The Infection. 
  • Children Neonates: 0.6 Ml Of Drops Every 4 Hr; 
  • 1 Month-2 Yr: 1/4 Adult Dose; 
  • 2-10 Yr: 1/2 Adult Dose. 

By IM Or IV Inj: 

  • Adults: IM Inj: 500 Mg-1500 Mg Every 4-6 Hr, Or As Indicated By The Severity Of The Infection By IV Infusion: In Severe Infections In Adults Up To 12 Gm May Be Administered. 

By IM Or IV Inj Or IV Infusion: 

  • Children Neonates: 75 Mg Every 8 Hr; 
  • 1 Month-2 Yr: 1/4 Adult Dose; 
  • 2-10 Yr: 1/2 Adult Dose.

Content

  • Cap 250mg: Ampicillin 125mg, Cloxacillin 125mg.
  • Cap 500mg: Ampicillin 250mg, Cloxacillin 250mg.
  • Drop Neonatal 90mg: Per 0.6 ml: Ampicillin 60mg, Cloxacillin 30mg; Powder For Reconstit

Pregnancy

Not Known To Be Harmful

Stability

  • Broad-spectrum Penicillin
  • Penicillinase-resistant Penicillin

Contra Indications

  • History Of Flucloxacillin Associated Jaundice/hepatic Dysfunction, Hypersensitivity To Penicillins, Cephalosporins Or Other Beta-lactams.

Precautions

  • History Of Flucloxacillin Associated Jaundice/hepatic Dysfunction, Hypersensitivity To Penicillins, Cephalosporins Or Other Beta-lactams.

Lactation

  • Not Known to Be Harmful

Side Effects

  • Hypersensitivity Reaction
  • Gi Disturbance
  • Nausea And Vomiting. Rarely Hepatitis
  • Cholestatic Jaundice
  • Haematological And Cns Effects
  • Pseudomembranous Colitis
  • Increased Inr
  • Stevens-johnson's Syndrome
  • Toxic Epidermal Necrosis.

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