Mitoxantrone
Therapeutic Group
Anti-neoplasticsIndication Dosage
Mitoxantrone is a medication primarily indicated for the treatment of certain types of cancer, including metastatic breast cancer, acute nonlymphocytic leukemia (ANLL), and advanced prostate cancer. Additionally, it is used in the management of multiple sclerosis (MS) to reduce the frequency of relapses and delay disability progression in selected patients with relapsing-remitting or secondary progressive forms of the disease. Mitoxantrone works by interfering with the growth and replication of cancer cells or by modulating the immune system in the case of MS, providing a valuable therapeutic option in these conditions when prescribed and monitored by a healthcare professional.
Metastatic Breast Cancer, Non-Hodgkin's Lymphoma, Adult Acute Non-lymphocytic Leukaemia, Non-resectable Primary Hepatocellular Carcinoma, Ovarian Carcinoma:
By IV Infusion:
- Adult: 12 Mg/m2 Every 3 Months.
Content
- Inf /Inj 20mg: mitoxantrone Hci 20mg; Solutionn In Vial.
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
- Dna-reactive Cytotoxic Antibiotic
Contra Indications
- None Known
Precautions
- None Known
Lactation
- Contraindicated. Discontinue Breast-feeding
Side Effects
- Abdominal Pain
- Alopecia
- Amenorrhoea
- Anorexia
- Anxiety
- Blue Discoloration Of Nails And Skin
- Bone-marrow Suppression
- Confusion
- Constipation
- Diarrhoea
- Cardiotoxicity
- Drowsiness
- Dyspnea
- Extravasation
- Gi Bleeding
- Hyperuricaemia
- Myelosuppression
- Nausea
- Oral Mucositis
- Paraesthesia
- Thromboembolism
- Transient Blue-green Discoloration Of Urine
- Tumourlysis Syndrome
- Vomiting