Nabumetone

Therapeutic Group

Anti-inflammatory And Anti-rheumatic Products

Indication Dosage

Pain And Inflammation In Osteoarthritis And Rheumatoid Arthritis: 

  • Adult: 1 G Once Daily At Night 
  • Elderly: 0.5-1 G Daily 

Pain And Inflammation In Osteoarthritis And Rheumatoid Arthritis With Severe And Persistent Symptoms: 

  • Adult: 0.5-1 In The Morning And 1 G At Night 
  • Elderly: 0.5-1 G Daily

Content

  • Tab 500mg: Nabumetone 500mg

Pregnancy

Contraindicated In Pregnancy

Stability

  • Naphthylalkanone

Contra Indications

  • Active Gi Bleeding Or Ulceration, History Of Gi Bleeding Or Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage Or Ulceration (two Or More Distinct Episodes), Severe Heart Failure, Aspirin/anti-inflammatory Induced Allergy, Hepatic And Renal Failure; Creatinine Clearance <20 Ml/min.

Precautions

  • Active Gi Bleeding Or Ulceration, History Of Gi Bleeding Or Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage Or Ulceration (two Or More Distinct Episodes), Severe Heart Failure, Aspirin/anti-inflammatory Induced Allergy, Hepatic And Renal Failure; Creatinine Clearance <20 Ml/min.

Lactation

  • Contraindicated

Side Effects

  • Abdominal Pain
  • Angioedema
  • Blood Disorders
  • Bronchospasm
  • Colitis
  • Crohn's Disease
  • Depression
  • Diarrhoea
  • Dizziness
  • Drowsiness
  • Fluid Retention
  • Gi Bleeding And Ulceration
  • Gi Disturbances
  • Haematuria
  • Headache
  • Hearing Disturbances
  • Hypersensitivity Reactions
  • Nausea
  • Nervousness
  • Photosensitivity
  • Raised Blood Pressure
  • Rashes
  • Renal Failure
  • Tinnitus
  • Vertigo.
  • Rare: Hepatic Damage
  • Interstitial Fibrosis Associated With Nsaids
  • Stevens-johnson Syndrome
  • Toxic Epidermal Necrolysis
  • Visual Disturbances
  • Exacerbation Of Symptoms In Asthma
  • Thrombocytopenia
  • Aseptic Meningitis
  • Cns Disturbances.

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