Olanzapine And Fluoxetine

Therapeutic Group

Anti-depressants

Indication Dosage

Olanzapine and Fluoxetine is a medication that doctors use to treat a specific mental health condition called "bipolar depression." It's for people who have periods of extreme sadness and high energy (mania) as part of their bipolar disorder.

Treatment Resistant Depression, Depression Associated With Bipolar 1 Disorder: 

  • Adult: Initially25 Mg/6 Mg Per Day In Evening Then Increase Gradually If Needed; Max 75 Mg/18 Mg Per Day.

Content

  • Cap /Tab: Olanzapine 6mg, Fluoxetine Hydrochloride 25mg.
  • Cap /Tab: Olanzapine 3mg, Fluoxetine Hydrochloride 25mg.
  • Cap: Olanzapine 12mg, Fluoxetine Hydrochloride 25mg.

Pregnancy

Avoid Unless Potential Benefit Outweighs Risk

Stability

  • SSRIs
  • Thienobenzodiazepine

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Contraindicated, Avoid

Side Effects

  • Agitation
  • Anxiety
  • Arthralgia
  • Blood Disorders
  • Confusion
  • Convulsions
  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Fatigue
  • Headache
  • Increased Appetite
  • Insomnia
  • Myalgia
  • Oedema
  • Postural Hypotension
  • Tremor
  • Weight Changes
  • Hallucinations
  • Mania
  • Movement Disorders
  • Syncope
  • Dysarthria
  • Hypersalivation
  • Hyponatraemia
  • Inappropriate Secretion Of Antidiuretic Hormone
  • Sedation During Initial Treatment
  • Rare: Aggression
  • Myoclonus
  • Pancreatitis
  • Angle-closure Glaucoma
  • Stevens-johnson Syndrome
  • Suicidal Behavior
  • Toxic Epidermal Necrolysis