Reteplase

Therapeutic Group

Anti-thrombotic Agents

Indication Dosage

Reteplase is a medication used to treat serious blood clots in the body. It's typically given to people who are experiencing a heart attack or a condition called deep vein thrombosis. Reteplase helps dissolve these dangerous clots, improving blood flow and reducing the risk of serious complications. It's an important medicine used in emergency situations to save lives when blood clots become a problem.

By IV Inj: 

  • Adult: 10 Units, Initiated Within 12 Hours Of Onset Of Symptoms, Followed By 10 Units After 30 Minutes 
  • Children: Not Recommended.

Content

  • Inj: Per Vial: Reteplase 10 Iu; Powder For Reconstitution In 10 ml Of Sterile Water.

Pregnancy

Caution Advised

Stability

  • Fibrinolytic

Contra Indications

  • Severe Renal Or Liver Dysfunction, Acute Pancreatitis, Pericarditis, Bacterial Endocarditis, Within 3 Months Of Severe Bleeding, Surgery Or Major Trauma, Haemorrhagic Diathesis,intracranial Neoplasm, Arterio-venous Malformation, Cva, Within 10 Days Of External Heart Massage, Uncontrolled Hypertension, Active Peptic Ulcer, Portal Hypertension,

Precautions

  • Severe Renal Or Liver Dysfunction, Acute Pancreatitis, Pericarditis, Bacterial Endocarditis, Within 3 Months Of Severe Bleeding, Surgery Or Major Trauma, Haemorrhagic Diathesis,intracranial Neoplasm, Arterio-venous Malformation, Cva, Within 10 Days Of External Heart Massage, Uncontrolled Hypertension, Active Peptic Ulcer, Portal Hypertension,

Lactation

  • Caution Advised

Side Effects

  • Heart Failure
  • Arrhythmias
  • Cardiac Arrest
  • Cardiogenic Shock
  • Haemorrhage
  • Intracranial Bleeding
  • Ischaemia
  • Hypotension
  • Reinfarction
  • Injection Site Reactions.

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