Trazodone

Therapeutic Group

Anti-depressants

Indication Dosage

Trazodone is indicated for the treatment of major depressive disorder (MDD) in adults. It may also be prescribed off-label for other conditions such as insomnia, and anxiety disorders, and as an adjunctive therapy in certain chronic pain conditions. It should only be used as directed by a healthcare professional.

Depressive Illness (particularly Where Sedation Is Required): 

  • Adult: Initially 150 Mg Daily In Divided Doses, Dose To Be Taken After Food, Alternatively Initially 150 Mg Once Daily At Bedtime, Increased If Necessary To 300 Mg Daily; Increased If Necessary To 600 Mg Daily In Divided Doses, Higher Dose For Use In Hospital Patients Only 
  • Elderly: Start With a Reduced Dose Then Increase 

Anxiety: 

  • Adult: 75 Mg Daily, Increased If Necessary To 300 Mg Daily

Content

  • Tab 50mg /100mg: Trazodone 50mg /100mg.
  • Drop Per 5 ml: Trazodone 50mg.

Pregnancy

Consult with Doctor Or Caution Advised

Stability

  • Triazolopyridine

Contra Indications

  • Acute Porphyrias, Arrhythmias, During The Manic Phase Of Bipolar Disorder, Heart Block, Immediate Recovery Period After Myocardial Infarction

Precautions

  • Acute Porphyrias, Arrhythmias, During The Manic Phase Of Bipolar Disorder, Heart Block, Immediate Recovery Period After Myocardial Infarction

Lactation

  • Consult with Doctor Or Caution Advised

Side Effects

  • Abdominal Pain
  • Agitation
  • Alopecia
  • Anorexia
  • Anxiety
  • Arrhythmia
  • Blurred Vision
  • Fatigue
  • Hypertension
  • Mydriasis
  • Restlessness
  • Confusion
  • Convulsions
  • Delusions
  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Dysarthria
  • Ecg Changes
  • Flushing
  • Galactorrhoea
  • Gynaecomastia
  • Haematological Reactions
  • Hallucinations
  • Heart Block
  • Hepatic Reactions
  • Hypomania
  • Hyponatraemia
  • Irritability
  • Mania
  • Oedema
  • Paraesthesia
  • Photosensitivity
  • Postural Hypotension
  • Pruritus
  • Rash
  • Sexual Dysfunction
  • Sleep Disturbances
  • Stomatitis
  • Sudden Death Of Patients With Cardiac Disease
  • Suicidal Behavior
  • Sweating
  • Tachycardia
  • Taste Disturbance
  • Tinnitus
  • Tremor
  • Urinary Retention
  • Urticaria
  • Vomiting
  • Weight Changes.
  • Rare: Extrapyramidal Symptoms
  • Paralytic Ileus