Tretinoin

Therapeutic Group

Anti-neoplastics

Indication Dosage

Tretinoin is a medication commonly prescribed for the treatment of various dermatological conditions. It is primarily indicated for the management of acne, helping to reduce the formation of new acne lesions and improving the overall appearance of the skin. Tretinoin is also used to mitigate the signs of photoaging, such as fine lines, wrinkles, and uneven skin tone, by promoting skin cell turnover and collagen production. This medication works by unclogging pores, enhancing skin exfoliation, and stimulating the renewal of skin cells.

Induction Of Remission In Acute Promyelocytic Leukaemia (untreated Patients, Relapsed Or Refractory): 

  • Adult: 45 Mg/m2 Daily In 2 Divided Doses Maximum Duration Of Treatment Is 90 Days, Consult Product Literature For Details Of Concomitant Chemotherapy

Content

  • Cap 10mg: Tretinoin 10mg

Pregnancy

Contraindicated.

Stability

  • Retinoid

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Contraindicated. Discontinue Breast-feeding

Side Effects

  • Alopecia
  • Anxiety
  • Arrhythmias
  • Benign Intracranial Hypertension
  • Bone Pain
  • Cheilitis
  • Confusion
  • Depression
  • Dizziness
  • Erythema
  • Flushing
  • Gi Disturbances
  • Genital Ulceration
  • Hearing Disturbances
  • Hypercalcaemia
  • Insomnia
  • Oedema
  • Pancreatitis
  • Paraesthesia
  • Pruritus
  • Raised Lipids
  • Raised Liver Enzymes
  • Raised Serum Creatinine
  • Rash
  • Retinoic Acidsyndrome
  • Shivering
  • Thromboembolism
  • Visual Disturbances

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