Generic Name
AmikacinPacks Price
- Inj100 mg(001455): 1 Vialx2 ml: 78.20: 92.00
- Inj250 mg(004022): 1 Vial: 97.75: 115.00
- Inj500 mg(004023): 5 ml: 170.00: 200.00
Negramin
Therapeutic Group
Aminoglycoside Anti-bacterialsIndication Dosage
Serious Gram-negative Infections Resistant To Gentamicin Including, Bone & Joint Infections, Lower Respiratory Tract Infections, Septicemia And Meningitis:
By IM Inj, Or By Slow IV Inj, Or By IV Infusion:
- Adult: 15 Mg/kg Daily In 2 Divided Doses, Increased To22.5 Mg/kg Daily In 3 Divided Doses For Up To 10 Days, Higher Dose To Be Used In Severe Infections; Maximum1.5 G Per Day; Maximum 15 G Per Course
- Children: Neonates: Initially 10 Mg/kg Then 15 Mg/kg Daily In Two Divided Doses; Others Same As Adults.
By IV Infusion:
- Adult: Initially 15 Mg/kg (max. Per Dose 1.5 G Once Daily), Dose To Be Adjusted According To Serum-amikacin Concentration; Maximum 15 G Per Course
Content
- Inj 25mg /50mg /100mg / 250mg /500mg: Per Vial: Amikacin (as Sulphate) 25mg /50mg /100mg / 250mg /500mg.
Pregnancy
Contraindicated
Stability
- Aminoglycoside Antibiotics
Contra Indications
- Myasthenia Gravis.
Precautions
- Myasthenia Gravis.
Lactation
- Contraindicated
Side Effects
- Auditory Damage
- Impaired Neuromuscular Transmission
- Irreversible Ototoxicity
- Nephrotoxicity
- Transient Myasthenic Syndrome In Patients With Normal Neuromuscular Function With Large Doses Given During Surgery
- Vestibular Damage.
- Rare: Antibiotic-associated Colitis
- Electrolyte Disturbances
- Hypocalcaemia
- Hypokalaemia
- Hypomagnesaemia On Prolonged Therapy
- Nausea
- Peripheral Neuropathy
- Stomatitis
- Vomiting
- Blood Disorders
- Cns Effects
- Convulsions
- Encephalopathy
- Rash
Available Brands
Author
Shahid Arif