Trastuzumab emtansine, commonly known as T-DM1, is a medication indicated for the treatment of HER2-positive breast cancer. It is prescribed for patients who have previously received trastuzumab (Herceptin) and a taxane chemotherapy, either separately or in combination, and whose cancer has progressed despite these treatments. T-DM1 works by targeting HER2 receptors on cancer cells, delivering a potent chemotherapy drug directly to the tumor, thereby inhibiting cancer cell growth and reducing the spread of the disease.
Monotherapy For The Treatment Of Her2-positive, Unresectable, Locally Advanced Or Metastatic Breast Cancer, In Adult Patients Who Have Previously Received Trastuzumab Separately Or In Combination, Or Who Have Developed Disease Recurrence During Or Within 6 Months Of Completing Adjuvant Therapy:
By IV Infusion:
Adults: 4mg/kg Iv Over 90 Mins. Maintenance: 2mg/kg IV over 30 Min Every Week.
Content
Inf 440mg: Per 20 ml
Trastuzumab 440mg.
Inf 160mg: Trastuzumab 160mg.
Inf 100mg: Trastuzumab 100mg.
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
Monoclonal Antibody
Contra Indications
Hypersensitivity To Murine Proteins, Severe Dyspnoea.
Precautions
Hypersensitivity To Murine Proteins, Severe Dyspnoea.